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Cardiovascular system
Cardiovascular system / Patent ductus arteriosus
  dinoprostone Hospital only
  Vaginal device
Propess (Ferring Pharmaceuticals Ltd) Hospital only
  Vaginal gel
Prostin E2 (Pfizer Ltd) Hospital only
Cardiovascular system / Arrhythmias
  acebutolol Not approved for prescribing
  adenosine Hospital only
  Solution for injection
Adenosine (Non-proprietary) Hospital only
Adenocor (Sanofi) Hospital only
  Solution for infusion
Adenosine (Non-proprietary) Hospital only
Adenoscan (Sanofi) Hospital only
  amiodarone hydrochloride Specialist knowledge/initiation
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Amiodarone hydrochloride (Non-proprietary) Hospital only
Cordarone X (Sanofi) Hospital only
  atenolol Joint formulary choice
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Oral solution
Atenolol (Non-proprietary) Joint formulary choice
  Solution for injection
Tenormin (Atnahs Pharma UK Ltd) Hospital only
  atropine sulfate Hospital only
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Atropine sulfate (Non-proprietary) Hospital only
  digoxin Specialist knowledge/initiation
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Digoxin (Non-proprietary) Hospital only
  disopyramide Hospital only
  Modified-release tablet
Rythmodan Retard (Neon Healthcare Ltd) Hospital only
  dronedarone Hospital only NICE TA197
  esmolol hydrochloride Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Esmolol hydrochloride (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Brevibloc (Baxter Healthcare Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for infusion
Brevibloc (Baxter Healthcare Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  flecainide acetate Specialist knowledge/initiation
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  lidocaine hydrochloride Hospital only
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Lidocaine hydrochloride (Non-proprietary) Hospital only
  metoprolol tartrate Joint formulary choice
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Betaloc (Recordati Pharmaceuticals Ltd) Hospital only
  mexiletine Not approved for prescribing NICE TA748
  nadolol Not approved for prescribing
  propafenone hydrochloride Hospital only
  propranolol hydrochloride Specialist knowledge/initiation
  Modified-release capsule
Bedranol SR (Almus Pharmaceuticals Ltd, Sandoz Ltd) Specialist knowledge/initiation
Beta-Prograne (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Half Beta-Prograne (Accord-UK Ltd, Teva UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
  Oral solution
Propranolol hydrochloride (Non-proprietary) Specialist knowledge/initiation
  sotalol hydrochloride Specialist knowledge/initiation
  verapamil hydrochloride Specialist knowledge/initiation
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

  Modified-release tablet
Half Securon (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

Securon SR (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

Vera-Til SR (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

Verapress MR (Dexcel-Pharma Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

  Oral solution
Verapamil hydrochloride (Non-proprietary) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

  Solution for injection
Securon (Viatris UK Healthcare Ltd) Hospital only
  vernakalant Non-formulary at HHFT and not suitable for primary care prescribing
Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

  Solution for infusion
Brinavess (Correvio UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Cardiovascular system / Hypertension
  acebutolol Not approved for prescribing
  aliskiren Not approved for prescribing
  amiloride hydrochloride Joint formulary choice
  Oral solution
Amiloride hydrochloride (Non-proprietary) Joint formulary choice
  amlodipine Joint formulary choice
  Oral solution
Amlodipine (Non-proprietary) Not approved for prescribing
  amlodipine with valsartan Not approved for prescribing
  atenolol Joint formulary choice
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Oral solution
Atenolol (Non-proprietary) Joint formulary choice
  Solution for injection
Tenormin (Atnahs Pharma UK Ltd) Hospital only
  azilsartan medoxomil Not approved for prescribing
  bendroflumethiazide Joint formulary choice
  bisoprolol fumarate Specialist knowledge/initiation
  candesartan cilexetil Joint formulary choice
  captopril Not approved for prescribing
  Oral solution
Captopril (Non-proprietary) Not approved for prescribing
  carvedilol Specialist knowledge/initiation
  celiprolol hydrochloride Not approved for prescribing
  chlortalidone Joint formulary choice
  clonidine hydrochloride Specialist knowledge/initiation
Clonidine for the management of ADHD is hospital only

Clonidine for the management of ADHD should only be prescribed in secondary care.

  co-amilozide Not approved for prescribing
  co-tenidone Not approved for prescribing
  diltiazem hydrochloride Joint formulary choice
  Modified-release tablet
Diltiazem hydrochloride (Non-proprietary) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Retalzem (Kent Pharma (UK) Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Tildiem (Sanofi) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Tildiem Retard (Sanofi) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  Modified-release capsule
Adizem-SR (Napp Pharmaceuticals Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Adizem-XL (Napp Pharmaceuticals Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Angitil SR (Ethypharm UK Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Angitil XL (Ethypharm UK Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Slozem (Zentiva Pharma UK Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Tildiem LA (Sanofi) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Viazem XL (Thornton & Ross Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Zemtard XL (Galen Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  doxazosin Joint formulary choice
  Modified-release tablet
Cardura XL (Viatris UK Healthcare Ltd) Not approved for prescribing
Doxadura XL (Dexcel-Pharma Ltd) Not approved for prescribing
Larbex XL (Teva UK Ltd) Not approved for prescribing
Raporsin XL (Accord-UK Ltd) Not approved for prescribing
  enalapril maleate Joint formulary choice
  enalapril with hydrochlorothiazide Not approved for prescribing
  eprosartan Not approved for prescribing
  esmolol hydrochloride Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Esmolol hydrochloride (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Brevibloc (Baxter Healthcare Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for infusion
Brevibloc (Baxter Healthcare Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  felodipine Not approved for prescribing
  Modified-release tablet
Cardioplen XL (Chiesi Ltd) Not approved for prescribing
Felendil XL (Teva UK Ltd) Not approved for prescribing
Parmid XL (Sandoz Ltd) Not approved for prescribing
Vascalpha (Accord-UK Ltd) Not approved for prescribing
  fosinopril sodium Not approved for prescribing
  furosemide Joint formulary choice
  Oral solution
Furosemide (Non-proprietary) Joint formulary choice
Frusol (Rosemont Pharmaceuticals Ltd) Joint formulary choice
  Solution for injection
Furosemide (Non-proprietary) Hospital only
  hydralazine hydrochloride Specialist knowledge/initiation
  hydrochlorothiazide Not approved for prescribing
  imidapril hydrochloride Not approved for prescribing
  indapamide Joint formulary choice
  Modified-release tablet
Alkapamid XL (HBS Healthcare Ltd) Joint formulary choice
Cardide SR (Teva UK Ltd) Joint formulary choice
Natrilix SR (Servier Laboratories Ltd) Joint formulary choice
  indoramin Not approved for prescribing
  irbesartan Specialist knowledge/initiation
  irbesartan with hydrochlorothiazide Not approved for prescribing
  labetalol hydrochloride Joint formulary choice
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Labetalol hydrochloride (Non-proprietary) Hospital only
  lacidipine Not approved for prescribing
  lercanidipine hydrochloride Not approved for prescribing
  lisinopril Joint formulary choice
  Oral solution
Lisinopril (Non-proprietary) Joint formulary choice
  lisinopril with hydrochlorothiazide Not approved for prescribing
  losartan potassium Joint formulary choice
  losartan with hydrochlorothiazide Not approved for prescribing
  methyldopa Specialist knowledge/initiation
  metolazone Specialist knowledge/initiation
  metoprolol tartrate Joint formulary choice
  Solution for injection
Betaloc (Recordati Pharmaceuticals Ltd) Hospital only
  minoxidil Specialist knowledge/initiation
  moxonidine Specialist knowledge/initiation
  nadolol Not approved for prescribing
  nebivolol Not approved for prescribing
  nicardipine hydrochloride Not approved for prescribing
  Solution for infusion
Nicardipine hydrochloride (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  nifedipine Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  Modified-release tablet
Adalat LA (Bayer Plc) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Adanif XL (Advanz Pharma) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Adipine MR (Chiesi Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Adipine XL (Chiesi Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Fortipine LA (Advanz Pharma) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Nifedipress MR (Dexcel-Pharma Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Tensipine MR (Genus Pharmaceuticals Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Valni Retard (Tillomed Laboratories Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Valni XL (Zentiva Pharma UK Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  Modified-release capsule
Coracten SR (Teofarma S.r.l.) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Coracten XL (Teofarma S.r.l.) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  Oral drops
Nifedipine (Non-proprietary) Not approved for prescribing
  olmesartan medoxomil Not approved for prescribing
  olmesartan with amlodipine Not approved for prescribing
  olmesartan with amlodipine and hydrochlorothiazide Specialist knowledge/initiation
  Oral tablet
Sevikar HCT (Daiichi Sankyo UK Ltd) Specialist knowledge/initiation
  olmesartan with hydrochlorothiazide Not approved for prescribing
  perindopril arginine Not approved for prescribing
  perindopril arginine with indapamide Not approved for prescribing
  perindopril erbumine Joint formulary choice
  pindolol Not approved for prescribing
  prazosin Not approved for prescribing
  propranolol hydrochloride Specialist knowledge/initiation
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Modified-release capsule
Bedranol SR (Almus Pharmaceuticals Ltd, Sandoz Ltd) Specialist knowledge/initiation
Beta-Prograne (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Half Beta-Prograne (Accord-UK Ltd, Teva UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
  Oral solution
Propranolol hydrochloride (Non-proprietary) Specialist knowledge/initiation
  quinapril Not approved for prescribing
  quinapril with hydrochlorothiazide Not approved for prescribing
  ramipril Joint formulary choice
  Oral solution
Ramipril (Non-proprietary) Joint formulary choice
  ramipril with felodipine Not approved for prescribing
  spironolactone Specialist knowledge/initiation
  telmisartan Not approved for prescribing
  telmisartan with hydrochlorothiazide Not approved for prescribing
  terazosin Not approved for prescribing
  Form unstated
Hytrin (Advanz Pharma) Not approved for prescribing
  timolol maleate Not approved for prescribing
  timolol with bendroflumethiazide Not approved for prescribing
  torasemide Not approved for prescribing
  trandolapril Not approved for prescribing
  triamterene with chlortalidone Not approved for prescribing
  valsartan Joint formulary choice
  Oral solution
Diovan (Novartis Pharmaceuticals UK Ltd) Joint formulary choice
  valsartan with hydrochlorothiazide Not approved for prescribing
  verapamil hydrochloride Specialist knowledge/initiation
  Modified-release tablet
Half Securon (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Securon SR (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

Vera-Til SR (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Verapress MR (Dexcel-Pharma Ltd) Specialist knowledge/initiation
  Oral solution
Verapamil hydrochloride (Non-proprietary) Specialist knowledge/initiation
  Solution for injection
Securon (Viatris UK Healthcare Ltd) Hospital only
  xipamide Not approved for prescribing
Cardiovascular system / Portal hypertension
  propranolol hydrochloride Specialist knowledge/initiation
  Modified-release capsule
Bedranol SR (Almus Pharmaceuticals Ltd, Sandoz Ltd) Specialist knowledge/initiation
Beta-Prograne (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Half Beta-Prograne (Accord-UK Ltd, Teva UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
  Oral solution
Propranolol hydrochloride (Non-proprietary) Specialist knowledge/initiation
Cardiovascular system / Pulmonary hypertension
  ambrisentan Hospital only
  bosentan Non-formulary at HHFT and not suitable for primary care prescribing
  epoprostenol Hospital only
  Powder and solvent for solution for infusion
Flolan (GlaxoSmithKline UK Ltd) Hospital only
  iloprost Hospital only
  macitentan Non-formulary at HHFT and not suitable for primary care prescribing
  riociguat Non-formulary at HHFT and not suitable for primary care prescribing
  selexipag Non-formulary at HHFT and not suitable for primary care prescribing
  sildenafil Hospital only
  Oral suspension
Revatio (Viatris UK Healthcare Ltd) Hospital only
  Solution for injection
Revatio (Viatris UK Healthcare Ltd) Hospital only
  tadalafil Hospital only
Cardiovascular system / Hypertension associated with phaeochromocytoma
  phenoxybenzamine hydrochloride Not approved for prescribing
  propranolol hydrochloride Specialist knowledge/initiation
  Modified-release capsule
Bedranol SR (Almus Pharmaceuticals Ltd, Sandoz Ltd) Specialist knowledge/initiation
Beta-Prograne (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Half Beta-Prograne (Accord-UK Ltd, Teva UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
  Oral solution
Propranolol hydrochloride (Non-proprietary) Specialist knowledge/initiation
Cardiovascular system / Hypertensive crises
  hydralazine hydrochloride Specialist knowledge/initiation
  Powder for solution for injection
Hydralazine hydrochloride (Non-proprietary) Hospital only
  labetalol hydrochloride Hospital only
  Solution for injection
Labetalol hydrochloride (Non-proprietary) Hospital only
  sodium nitroprusside Hospital only
  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) Hospital only
Cardiovascular system / Hypotension and shock
  angiotensin II Non-formulary at HHFT and not suitable for primary care prescribing
Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

  Solution for infusion
Giapreza (PAION Deutschland GmbH) Non-formulary at HHFT and not suitable for primary care prescribing
  dobutamine Hospital only
  Solution for infusion
Dobutamine (Non-proprietary) Hospital only
  dopamine hydrochloride Hospital only
  Solution for infusion
Dopamine hydrochloride (Non-proprietary) Hospital only
  ephedrine hydrochloride Hospital only
  Solution for injection
Ephedrine hydrochloride (Non-proprietary) Hospital only
  metaraminol Hospital only
  Solution for injection
Metaraminol (Non-proprietary) Hospital only
  midodrine hydrochloride Specialist knowledge/initiation
  noradrenaline/norepinephrine Hospital only
  Solution for infusion
Noradrenaline/norepinephrine (Non-proprietary) Hospital only
  phenylephrine hydrochloride Hospital only
  Solution for injection
Phenylephrine hydrochloride (Non-proprietary) Hospital only
  sodium nitroprusside Hospital only
  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) Hospital only
Cardiovascular system / Vascular disease
  cilostazol Not approved for prescribing NICE TA223
  inositol nicotinate Not approved for prescribing NICE TA223
Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

  naftidrofuryl oxalate Specialist knowledge/initiation NICE TA223
  nifedipine Joint formulary choice
  Oral drops
Nifedipine (Non-proprietary) Not approved for prescribing
  oxerutins Not approved for prescribing
  pentoxifylline Not approved for prescribing NICE TA223
Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

  Modified-release tablet
Trental (Neuraxpharm UK Ltd) Not approved for prescribing
  prazosin Not approved for prescribing
Cardiovascular system / Vein malformations
  sodium tetradecyl sulfate Not approved for prescribing
  Solution for injection
Fibro-Vein (STD Pharmaceutical Products Ltd) Not approved for prescribing
Cardiovascular system / Cardiomyopathy
  mavacamten Non-formulary at HHFT and not suitable for primary care prescribing NICE TA913
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  Oral capsule
Camzyos (Bristol-Myers Squibb Pharmaceuticals Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Cardiovascular system / Cardiac diagnostic procedures and surgeries
  dobutamine Hospital only
  Solution for infusion
Dobutamine (Non-proprietary) Hospital only
Cardiovascular system / Blocked catheters and lines
  epoprostenol Hospital only
  Powder and solvent for solution for infusion
Flolan (GlaxoSmithKline UK Ltd) Hospital only
  heparin (unfractionated) Hospital only
  Solution for injection
Heparin (unfractionated) (Non-proprietary) Hospital only
  Infusion
Heparin (unfractionated) (Non-proprietary) Hospital only
  Form unstated
Heparin (unfractionated) (Non-proprietary) Hospital only
  urokinase Hospital only
  Powder for solution for injection
Syner-KINASE (Syner-Med (Pharmaceutical Products) Ltd) Hospital only
Cardiovascular system / Thromboembolism
  acenocoumarol Specialist knowledge/initiation
  alteplase Hospital only NICE TA264
  Powder and solvent for solution for injection
Actilyse (Boehringer Ingelheim Ltd) Hospital only
  Powder and solvent for solution for infusion
Actilyse (Boehringer Ingelheim Ltd) Hospital only
  andexanet alfa Hospital only NICE TA697
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  Powder for solution for infusion
Ondexxya (AstraZeneca UK Ltd) Hospital only
  apixaban Specialist knowledge/initiation NICE TA245
NICE TA275
NICE TA341
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

Change of formulary status from Amber (shared care) to Amber (specialist knowledge/initiation)

February 2020 - the Joint Prescribing Group (JPG) agreed to approve the change of formulary status for apixaban, dabigatran, edoxaban and rivaroxaban from Amber (shared care) to Amber (specialist knowledge/initiation) as these drugs are now commonly initiated in primary care. 'Transfer of care' documents are still available to provide prescribing and monitoring guidance for these drugs. 

  argatroban monohydrate Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for infusion
Argatroban monohydrate (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Exembol (Mitsubishi Tanabe Pharma Europe Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  aspirin Joint formulary choice
  Gastro-resistant tablet
Aspirin (Non-proprietary) Joint formulary choice
  bivalirudin Non-formulary at HHFT and not suitable for primary care prescribing
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  Powder for solution for infusion
Bivalirudin (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  clopidogrel Joint formulary choice NICE TA210
  dabigatran etexilate Specialist knowledge/initiation NICE TA157
NICE TA249
NICE TA327
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

Change of formulary status from Amber (shared care) to Amber (specialist knowledge/initiation)

February 2020 - the Joint Prescribing Group (JPG) agreed to approve the change of formulary status for apixaban, dabigatran, edoxaban and rivaroxaban from Amber (shared care) to Amber (specialist knowledge/initiation) as these drugs are now commonly initiated in primary care. 'Transfer of care' documents are still available to provide prescribing and monitoring guidance for these drugs. 

  dalteparin sodium Hospital only
Thromboprophylaxis

June 2020 - the JPG agreed to approve the addition of dalteparin to the joint formulary. Dalteparin should only be used in line with HUHFT policy on Thromboprophylaxis and treatment of VTE complications in COVID-19 infection.

  Solution for injection
Fragmin (Pfizer Ltd) Not approved for prescribing
  danaparoid sodium Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Danaparoid sodium (Non-proprietary) Not approved for prescribing
  dipyridamole Joint formulary choice NICE TA210
  Modified-release capsule
Attia (Dr Reddy's Laboratories (UK) Ltd) Joint formulary choice
  Oral suspension
Dipyridamole (Non-proprietary) Joint formulary choice
  edoxaban Specialist knowledge/initiation NICE TA354
NICE TA355
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

Change of formulary status from Amber (shared care) to Amber (specialist knowledge/initiation)

February 2020 - the Joint Prescribing Group (JPG) agreed to approve the change of formulary status for apixaban, dabigatran, edoxaban and rivaroxaban from Amber (shared care) to Amber (specialist knowledge/initiation) as these drugs are now commonly initiated in primary care. 'Transfer of care' documents are still available to provide prescribing and monitoring guidance for these drugs. 

  enoxaparin sodium Shared care guideline
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

A formal Shared Care Guideline (SCG) may be available

Happy to prescribe

If you are asked to continue treatment for a specific condition for which a shared care guideline is available and you are happy to prescribe in accordance with the guidance then take over the agreed responsibilities, including prescribing. Please obtain a copy of the SCG from secondary care or via the link below. 

Unhappy to prescribe

If sufficient information has not been provided and if you do not feel happy to continue to prescribe then it is advisable to refer the patient back to the specialist clinic. Please complete an inappropriate request communication form and send this as soon as possible to the contact provided in the form. 

  Solution for injection
Clexane (Sanofi) Shared care guideline
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

A formal Shared Care Guideline (SCG) may be available

Happy to prescribe

If you are asked to continue treatment for a specific condition for which a shared care guideline is available and you are happy to prescribe in accordance with the guidance then take over the agreed responsibilities, including prescribing. Please obtain a copy of the SCG from secondary care or via the link below. 

Unhappy to prescribe

If sufficient information has not been provided and if you do not feel happy to continue to prescribe then it is advisable to refer the patient back to the specialist clinic. Please complete an inappropriate request communication form and send this as soon as possible to the contact provided in the form. 

Inhixa (Techdow Pharma England Ltd) Shared care guideline
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

A formal Shared Care Guideline (SCG) may be available

Happy to prescribe

If you are asked to continue treatment for a specific condition for which a shared care guideline is available and you are happy to prescribe in accordance with the guidance then take over the agreed responsibilities, including prescribing. Please obtain a copy of the SCG from secondary care or via the link below. 

Unhappy to prescribe

If sufficient information has not been provided and if you do not feel happy to continue to prescribe then it is advisable to refer the patient back to the specialist clinic. Please complete an inappropriate request communication form and send this as soon as possible to the contact provided in the form. 

  fondaparinux sodium Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Fondaparinux sodium (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Arixtra (Viatris UK Healthcare Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  heparin (unfractionated) Hospital only
  Solution for injection
Heparin (unfractionated) (Non-proprietary) Hospital only
  Infusion
Heparin (unfractionated) (Non-proprietary) Hospital only
  Form unstated
Heparin (unfractionated) (Non-proprietary) Hospital only
  idarucizumab Hospital only
  Solution for infusion
Praxbind (Boehringer Ingelheim Ltd) Hospital only
  phenindione Specialist knowledge/initiation
  prasugrel Specialist knowledge/initiation NICE TA317
  rivaroxaban Specialist knowledge/initiation NICE TA170
NICE TA256
NICE TA261
NICE TA287
NICE TA335
NICE TA607
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

Change of formulary status from Amber (shared care) to Amber (specialist knowledge/initiation)

February 2020 - the Joint Prescribing Group (JPG) agreed to approve the change of formulary status for apixaban, dabigatran, edoxaban and rivaroxaban from Amber (shared care) to Amber (specialist knowledge/initiation) as these drugs are now commonly initiated in primary care. 'Transfer of care' documents are still available to provide prescribing and monitoring guidance for these drugs. 

  streptokinase Hospital only
  tinzaparin sodium Hospital only
  Solution for injection
Tinzaparin sodium (Non-proprietary) Hospital only
  urokinase Hospital only
  Powder for solution for injection
Syner-KINASE (Syner-Med (Pharmaceutical Products) Ltd) Hospital only
  warfarin sodium Specialist knowledge/initiation
  Oral suspension
Warfarin sodium (Non-proprietary) Specialist knowledge/initiation
Cardiovascular system / Oedema
  amiloride hydrochloride Joint formulary choice
  Oral solution
Amiloride hydrochloride (Non-proprietary) Joint formulary choice
  amiloride with bumetanide Not approved for prescribing
  bumetanide Joint formulary choice
  Oral solution
Bumetanide (Non-proprietary) Joint formulary choice
  chlortalidone Joint formulary choice
  co-amilofruse Not approved for prescribing
  diamorphine hydrochloride Hospital only
  Powder for solution for injection
Diamorphine hydrochloride (Non-proprietary) Hospital only
  furosemide Joint formulary choice
  Oral solution
Furosemide (Non-proprietary) Joint formulary choice
Frusol (Rosemont Pharmaceuticals Ltd) Joint formulary choice
  Solution for injection
Furosemide (Non-proprietary) Hospital only
  furosemide with triamterene Not approved for prescribing
  mannitol Hospital only NICE TA266
  Infusion
Mannitol (Non-proprietary) Hospital only
  Inhalation powder
Mannitol (Non-proprietary) Hospital only
Bronchitol (Chiesi Ltd) Hospital only
  metolazone Specialist knowledge/initiation
  spironolactone with furosemide Not approved for prescribing
  torasemide Not approved for prescribing
  triamterene Not approved for prescribing
  triamterene with chlortalidone Not approved for prescribing
  xipamide Not approved for prescribing
Cardiovascular system / Ascites
  chlortalidone Joint formulary choice
  co-amilozide Not approved for prescribing
  spironolactone Specialist knowledge/initiation
Cardiovascular system / Hyperlipidaemia
  acipimox Not approved for prescribing
  alirocumab Hospital only NICE TA393
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  Solution for injection
Praluent (Sanofi) Hospital only
  atorvastatin Joint formulary choice
  Chewable tablet
Lipitor (Viatris UK Healthcare Ltd) Not approved for prescribing
  bempedoic acid Specialist knowledge/initiation NICE TA694
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  bempedoic acid with ezetimibe Specialist knowledge/initiation NICE TA694
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  bezafibrate Joint formulary choice
  Modified-release tablet
Bezalip Mono (Teva UK Ltd) Joint formulary choice
  ciprofibrate Not approved for prescribing
  colesevelam hydrochloride Not approved for prescribing
  colestipol hydrochloride Not approved for prescribing
  colestyramine Not approved for prescribing
  evolocumab Hospital only NICE TA394
  Solution for injection
Repatha SureClick (Amgen Ltd) Hospital only
  ezetimibe Joint formulary choice NICE TA385
  fenofibrate Not approved for prescribing
  fluvastatin Not approved for prescribing
  gemfibrozil Not approved for prescribing
  icosapent ethyl Joint formulary choice NICE TA805
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  Oral capsule
Vazkepa (Amarin Pharmaceuticals Ireland Ltd) Joint formulary choice
  inclisiran Joint formulary choice NICE TA733
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

Inclisiran prescribing in primary care

Please note the North East London primary care prescribing pathway, including training resources for primary care prescribers are currently under development. Primary care prescribers are advised to wait for the prescribing pathway and training to be finalised prior to initiating inclisiran in line with NICE TA733

  Solution for injection
Leqvio (Novartis Pharmaceuticals UK Ltd) Joint formulary choice
Inclisiran prescribing in primary care

Please note the North East London primary care prescribing pathway, including training resources for primary care prescribers are currently under development. Primary care prescribers are advised to wait for the prescribing pathway and training to be finalised prior to initiating inclisiran in line with NICE TA733

  lomitapide Non-formulary at HHFT and not suitable for primary care prescribing
  nicotinic acid Not approved for prescribing
  omega-3-acid ethyl esters Not approved for prescribing
  pravastatin sodium Joint formulary choice
  rosuvastatin Not approved for prescribing
  simvastatin Joint formulary choice
  Oral suspension
Simvastatin (Non-proprietary) Joint formulary choice
  simvastatin with ezetimibe Not approved for prescribing
Cardiovascular system / Bleeding disorders
  emicizumab Not approved for prescribing
  Solution for injection
Hemlibra (Roche Products Ltd) Not approved for prescribing
  tranexamic acid Joint formulary choice
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Solution for injection
Tranexamic acid (Non-proprietary) Hospital only
Cyklokapron (Pfizer Ltd) Hospital only
Cardiovascular system / Coagulation factor deficiencies
  dried prothrombin complex Not approved for prescribing
  factor IX [Specialist drug] Not approved for prescribing
  Powder and solvent for solution for injection
Haemonine (Grifols UK Ltd) Not approved for prescribing
Replenine-VF (Bio Products Laboratory Ltd) Not approved for prescribing
  Powder and solvent for solution for infusion
BeneFIX (Pfizer Ltd) Not approved for prescribing
  factor VIII fraction, dried [Specialist drug] Non-formulary at HHFT and not suitable for primary care prescribing
  Powder and solvent for solution for injection
Factor VIII fraction, dried (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Advate (Takeda UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Elocta (Swedish Orphan Biovitrum Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Haemoctin (Grifols UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Nuwiq (Octapharma Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Octanate LV (Octapharma Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
ReFacto (Pfizer Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Voncento (CSL Behring UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  Powder and solvent for solution for infusion
Advate (Takeda UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Wilate 1000 (Octapharma Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Wilate 500 (Octapharma Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  factor VIII inhibitor bypassing fraction [Specialist drug] Not approved for prescribing
  Powder and solvent for solution for infusion
FEIBA Imuno (Takeda UK Ltd) Not approved for prescribing
  factor VIIa (recombinant) Hospital only
  Powder and solvent for solution for injection
NovoSeven (Novo Nordisk Ltd) Hospital only
  factor XIII fraction, dried [Specialist drug] Not approved for prescribing
  Powder and solvent for solution for injection
Fibrogammin P (CSL Behring UK Ltd) Not approved for prescribing
  fibrinogen, dried [Specialist drug] Not approved for prescribing
  fresh frozen plasma Hospital only
  protein C concentrate [Specialist drug] Non-formulary at HHFT and not suitable for primary care prescribing
  Powder and solvent for solution for injection
Ceprotin (Takeda UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Cardiovascular system / Subarachnoid haemorrhage
  nimodipine Hospital only
  Solution for infusion
Nimotop (Bayer Plc) Hospital only
Cardiovascular system / Heart failure
  bendroflumethiazide Not approved for prescribing
  bisoprolol fumarate Specialist knowledge/initiation
  candesartan cilexetil Joint formulary choice
  captopril Not approved for prescribing
  Oral solution
Captopril (Non-proprietary) Not approved for prescribing
  chlortalidone Joint formulary choice
  co-amilozide Not approved for prescribing
  co-flumactone Not approved for prescribing
  dapagliflozin Specialist knowledge/initiation NICE TA288
NICE TA390
NICE TA418
NICE TA679
NICE TA902
NICE TA775
Dapagliflozin and empagliflozin for heart failure

Dapagliflozin and empagliflozin for heart failure should only be initiated by or on recommendation of a specialist.

  Oral tablet
Forxiga (AstraZeneca UK Ltd) Specialist knowledge/initiation
  digoxin Specialist knowledge/initiation
  Solution for injection
Digoxin (Non-proprietary) Hospital only
  empagliflozin Specialist knowledge/initiation NICE TA390
NICE TA336
NICE TA773
NICE TA929
NICE TA942
Dapagliflozin and empagliflozin for heart failure

Dapagliflozin and empagliflozin for heart failure should only be initiated by or on recommendation of a specialist.

  Oral tablet
Jardiance (Boehringer Ingelheim Ltd) Specialist knowledge/initiation
  enalapril maleate Joint formulary choice
  enoximone Hospital only
  Solution for injection
Perfan (Macure Pharma UK Ltd) Hospital only
  eplerenone Specialist knowledge/initiation
  fosinopril sodium Not approved for prescribing
  glyceryl trinitrate Hospital only
  hydralazine hydrochloride Specialist knowledge/initiation
  isosorbide dinitrate Not approved for prescribing
Injection/infusion formulations

The injection/infusion formulation of this medicine is not recommended for prescribing in primary care (i.e. hospital only prescribing).

  Modified-release tablet
Isoket Retard (Forum Health Products Ltd) Not approved for prescribing
  Solution for injection
Isosorbide dinitrate (Non-proprietary) Hospital only
Isoket (Forum Health Products Ltd) Hospital only
  Solution for infusion
Isosorbide dinitrate (Non-proprietary) Hospital only
  isosorbide mononitrate Joint formulary choice
  Modified-release tablet
Isotard XL (Evolan Pharma AB) Joint formulary choice
Modisal XL (Ennogen Pharma Ltd) Joint formulary choice
Relosorb XL (Relonchem Ltd) Joint formulary choice
Xismox XL (Genus Pharmaceuticals Ltd) Joint formulary choice
  Modified-release capsule
Elantan LA (Forum Health Products Ltd) Joint formulary choice
Isodur XL (Galen Ltd) Joint formulary choice
Monomax SR (Martindale Pharmaceuticals Ltd) Joint formulary choice
  ivabradine Specialist knowledge/initiation NICE TA267
  lisinopril Joint formulary choice
  Oral solution
Lisinopril (Non-proprietary) Joint formulary choice
  losartan potassium Joint formulary choice
  milrinone Hospital only
  Solution for infusion
Milrinone (Non-proprietary) Hospital only
  nebivolol Not approved for prescribing
  perindopril arginine Not approved for prescribing
  perindopril erbumine Joint formulary choice
  prazosin Not approved for prescribing
  quinapril Not approved for prescribing
  ramipril Joint formulary choice
  Oral solution
Ramipril (Non-proprietary) Joint formulary choice
  sacubitril with valsartan Specialist knowledge/initiation NICE TA388
  sodium nitroprusside Hospital only
  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) Hospital only
  spironolactone Specialist knowledge/initiation
  valsartan Joint formulary choice
  Oral solution
Diovan (Novartis Pharmaceuticals UK Ltd) Joint formulary choice
  vericiguat Not approved for prescribing
Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

Cardiovascular system / Myocardial ischaemia
  acebutolol Not approved for prescribing
  amlodipine Joint formulary choice
  Oral solution
Amlodipine (Non-proprietary) Not approved for prescribing
  aspirin Joint formulary choice
  Gastro-resistant tablet
Aspirin (Non-proprietary) Joint formulary choice
  atenolol Joint formulary choice
  Oral solution
Atenolol (Non-proprietary) Joint formulary choice
  Solution for injection
Tenormin (Atnahs Pharma UK Ltd) Hospital only
  bisoprolol fumarate Specialist knowledge/initiation
  bivalirudin Non-formulary at HHFT and not suitable for primary care prescribing
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  Powder for solution for infusion
Bivalirudin (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  cangrelor Non-formulary at HHFT and not suitable for primary care prescribing
  Powder for solution for injection
Kengrexal (Chiesi Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  carvedilol Specialist knowledge/initiation
  diltiazem hydrochloride Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

  Modified-release tablet
Diltiazem hydrochloride (Non-proprietary) Joint formulary choice
Retalzem (Kent Pharma (UK) Ltd) Joint formulary choice
Tildiem (Sanofi) Joint formulary choice
Tildiem Retard (Sanofi) Joint formulary choice
  Modified-release capsule
Adizem-SR (Napp Pharmaceuticals Ltd) Joint formulary choice
Adizem-XL (Napp Pharmaceuticals Ltd) Joint formulary choice
Angitil SR (Ethypharm UK Ltd) Joint formulary choice
Brand prescribing recommended

Although generic prescribing is encouraged, there are some circumstances in which it is preferable to prescribe by brand name, these include where:

  • there are differences in bioavailability between brands of the same medicine
  • modified-release (MR) preparations that are not interchangeable
  • administration devices have different instructions for use and patient familiarity with one product is important
  • there are important differences in formulation between brands of the same medicine
  • branded and generic preparations have different licensed indications
  • products contain more than one ingredient and brand-name prescribing aids identification.

Please prescribe this product by brand.

Angitil XL (Ethypharm UK Ltd) Joint formulary choice
Slozem (Zentiva Pharma UK Ltd) Joint formulary choice
Tildiem LA (Sanofi) Joint formulary choice
Viazem XL (Thornton & Ross Ltd) Joint formulary choice
Zemtard XL (Galen Ltd) Joint formulary choice
  eptifibatide Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Eptifibatide (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for infusion
Eptifibatide (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  felodipine Not approved for prescribing
  Modified-release tablet
Cardioplen XL (Chiesi Ltd) Not approved for prescribing
Felendil XL (Teva UK Ltd) Not approved for prescribing
Parmid XL (Sandoz Ltd) Not approved for prescribing
Vascalpha (Accord-UK Ltd) Not approved for prescribing
  fondaparinux sodium Hospital only
  Solution for injection
Fondaparinux sodium (Non-proprietary) Hospital only
Arixtra (Viatris UK Healthcare Ltd) Hospital only
  glyceryl trinitrate Joint formulary choice
  Sublingual tablet
Glyceryl trinitrate (Non-proprietary) Joint formulary choice
  Sublingual spray
Glyceryl trinitrate (Non-proprietary) Joint formulary choice
Nitrolingual (Beaumont Pharma Ltd) Joint formulary choice
  Transdermal patch
Deponit (Forum Health Products Ltd) Joint formulary choice
Minitran (Viatris UK Healthcare Ltd) Joint formulary choice
Transiderm-Nitro (Novartis Pharmaceuticals UK Ltd) Joint formulary choice
  ivabradine Specialist knowledge/initiation NICE TA267
  metoprolol tartrate Joint formulary choice
  Solution for injection
Betaloc (Recordati Pharmaceuticals Ltd) Hospital only
  nadolol Not approved for prescribing
  nicardipine hydrochloride Not approved for prescribing
  Solution for infusion
Nicardipine hydrochloride (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
  nicorandil Specialist knowledge/initiation
  nifedipine Joint formulary choice
  Modified-release tablet
Adalat LA (Bayer Plc) Joint formulary choice
Adanif XL (Advanz Pharma) Joint formulary choice
Adipine MR (Chiesi Ltd) Joint formulary choice
Adipine XL (Chiesi Ltd) Joint formulary choice
Fortipine LA (Advanz Pharma) Joint formulary choice
Nifedipress MR (Dexcel-Pharma Ltd) Joint formulary choice
Tensipine MR (Genus Pharmaceuticals Ltd) Joint formulary choice
Valni Retard (Tillomed Laboratories Ltd) Joint formulary choice
Valni XL (Zentiva Pharma UK Ltd) Joint formulary choice
  Modified-release capsule
Coracten SR (Teofarma S.r.l.) Joint formulary choice
Coracten XL (Teofarma S.r.l.) Joint formulary choice
  Oral drops
Nifedipine (Non-proprietary) Not approved for prescribing
  pindolol Not approved for prescribing
  propranolol hydrochloride Specialist knowledge/initiation
  Modified-release capsule
Bedranol SR (Almus Pharmaceuticals Ltd, Sandoz Ltd) Specialist knowledge/initiation
Beta-Prograne (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Half Beta-Prograne (Accord-UK Ltd, Teva UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
  Oral solution
Propranolol hydrochloride (Non-proprietary) Specialist knowledge/initiation
  ranolazine Specialist knowledge/initiation
  Modified-release tablet
Ranexa (A. Menarini Farmaceutica Internazionale SRL) Specialist knowledge/initiation
  timolol maleate Not approved for prescribing
  tirofiban Non-formulary at HHFT and not suitable for primary care prescribing
  Infusion
Tirofiban (Non-proprietary) Non-formulary at HHFT and not suitable for primary care prescribing
Aggrastat (Correvio UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for infusion
Aggrastat (Correvio UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  verapamil hydrochloride Specialist knowledge/initiation
  Modified-release tablet
Half Securon (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Securon SR (Viatris UK Healthcare Ltd) Specialist knowledge/initiation
Verapamil for cluster headaches

Oral verapamil for cluster headaches should be prescribed under the explicit direction of a specialist only.

Vera-Til SR (Accord-UK Ltd, Tillomed Laboratories Ltd) Specialist knowledge/initiation
Verapress MR (Dexcel-Pharma Ltd) Specialist knowledge/initiation
  Oral solution
Verapamil hydrochloride (Non-proprietary) Specialist knowledge/initiation
  Solution for injection
Securon (Viatris UK Healthcare Ltd) Hospital only
Cardiovascular system / Acute coronary syndromes
  alteplase Hospital only NICE TA264
  Powder and solvent for solution for injection
Actilyse (Boehringer Ingelheim Ltd) Hospital only
  Powder and solvent for solution for infusion
Actilyse (Boehringer Ingelheim Ltd) Hospital only
  captopril Not approved for prescribing
  Oral solution
Captopril (Non-proprietary) Not approved for prescribing
  clopidogrel Joint formulary choice NICE TA210
  dalteparin sodium Not approved for prescribing
  Solution for injection
Fragmin (Pfizer Ltd) Not approved for prescribing
  enoxaparin sodium Hospital only
  Solution for injection
Clexane (Sanofi) Hospital only
Inhixa (Techdow Pharma England Ltd) Hospital only
  glyceryl trinitrate Hospital only
  Solution for infusion
Glyceryl trinitrate (Non-proprietary) Hospital only
Nitronal (Beaumont Pharma Ltd) Hospital only
  heparin (unfractionated) Hospital only
  Solution for injection
Heparin (unfractionated) (Non-proprietary) Hospital only
  Infusion
Heparin (unfractionated) (Non-proprietary) Hospital only
  Form unstated
Heparin (unfractionated) (Non-proprietary) Hospital only
  isosorbide dinitrate Not approved for prescribing
  Modified-release tablet
Isoket Retard (Forum Health Products Ltd) Not approved for prescribing
  Solution for injection
Isosorbide dinitrate (Non-proprietary) Hospital only
Isoket (Forum Health Products Ltd) Hospital only
  Solution for infusion
Isosorbide dinitrate (Non-proprietary) Hospital only
  isosorbide mononitrate Joint formulary choice
  Modified-release tablet
Isotard XL (Evolan Pharma AB) Joint formulary choice
Modisal XL (Ennogen Pharma Ltd) Joint formulary choice
Relosorb XL (Relonchem Ltd) Joint formulary choice
Xismox XL (Genus Pharmaceuticals Ltd) Joint formulary choice
  Modified-release capsule
Elantan LA (Forum Health Products Ltd) Joint formulary choice
Isodur XL (Galen Ltd) Joint formulary choice
Monomax SR (Martindale Pharmaceuticals Ltd) Joint formulary choice
  lisinopril Joint formulary choice
  Oral solution
Lisinopril (Non-proprietary) Joint formulary choice
  perindopril arginine Not approved for prescribing
  perindopril erbumine Joint formulary choice
  prasugrel Specialist knowledge/initiation NICE TA317
  ramipril Joint formulary choice
  Oral solution
Ramipril (Non-proprietary) Joint formulary choice
  streptokinase Hospital only
  tenecteplase Hospital only
  Powder and solvent for solution for injection
Metalyse (Boehringer Ingelheim Ltd) Hospital only
  ticagrelor Specialist knowledge/initiation NICE TA236
NICE TA420
  trandolapril Not approved for prescribing
  valsartan Joint formulary choice
  Oral solution
Diovan (Novartis Pharmaceuticals UK Ltd) Joint formulary choice
Cardiovascular system / Cardiac arrest
  adrenaline/epinephrine Hospital only
  Solution for injection
Adrenaline/epinephrine (Non-proprietary) Hospital only