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Blood and blood-forming organs
Blood and blood-forming organs / Hypoplastic, haemolytic, and renal anaemias
  darbepoetin alfa Hospital only NICE TA323
  Solution for injection
Aranesp (Amgen Ltd) Hospital only
Aranesp SureClick (Amgen Ltd) Hospital only
  eltrombopag Hospital only NICE TA293
  epoetin alfa Hospital only NICE TA323
  Solution for injection
Eprex (Janssen-Cilag Ltd) Hospital only
  epoetin beta Hospital only NICE TA323
  Solution for injection
NeoRecormon (Roche Products Ltd) Hospital only
  epoetin zeta Hospital only NICE TA323
  Solution for injection
Retacrit (Pfizer Ltd) Hospital only
  methoxy polyethylene glycol-epoetin beta Hospital only
  Solution for injection
Mircera (Roche Products Ltd) Hospital only
  oxymetholone Hospital only
  roxadustat Non-formulary at HHFT and not suitable for primary care prescribing NICE TA807
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

Blood and blood-forming organs / Sickle-cell disease
  VOXELOTOR Hospital only
  crizanlizumab Hospital only NICE TA743
Where positive NICE Technology Appraisal(s) apply to this medicine

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the relevant current NICE Technology Appraisal(s).

  hydroxycarbamide Shared care guideline
A formal Shared Care Guideline (SCG) may be available

Happy to prescribe

If you are asked to continue treatment for a specific condition for which a shared care guideline is available and you are happy to prescribe in accordance with the guidance then take over the agreed responsibilities, including prescribing. Please obtain a copy of the SCG from secondary care or via the link below. 

Unhappy to prescribe

If sufficient information has not been provided and if you do not feel happy to continue to prescribe then it is advisable to refer the patient back to the specialist clinic. Please complete an inappropriate request communication form and send this as soon as possible to the contact provided in the form. 

Blood and blood-forming organs / Atypical haemolytic uraemic syndrome and paroxysmal nocturnal haemoglobinuria
  eculizumab Non-formulary at HHFT and not suitable for primary care prescribing NICE HST1
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

Where negative or terminated NICE Technology Appraisal(s) apply to this medicine

This medicine is not recommended for use for the indication(s) specified in the relevant NICE Technology Appraisal(s) as currently NICE cannot recommend its use.

  Solution for infusion
Soliris (Alexion Pharma UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  pegcetacoplan Non-formulary at HHFT and not suitable for primary care prescribing NICE TA778
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  ravulizumab Non-formulary at HHFT and not suitable for primary care prescribing NICE TA698
NICE TA710
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

Blood and blood-forming organs / Iron deficiency anaemia
  ferric carboxymaltose Hospital only
Ferinject® (ferric carboxymaltose) reserved for those with high risk of developing hypersensitivity reactions

May 2022 - the Joint Prescribing Group (JPG) recommended for Ferinject® to be reserved for those with high risk of developing hypersensitivity reactions. Monofer® (ferric derisomaltose) would be the first choice parenteral iron for the treatment of iron deficiency at Homerton hospital.

  Solution for injection
Ferinject (Vifor Pharma UK Ltd) Hospital only
Ferinject® (ferric carboxymaltose) reserved for those with high risk of developing hypersensitivity reactions

May 2022 - the Joint Prescribing Group (JPG) recommended for Ferinject® to be reserved for those with high risk of developing hypersensitivity reactions. Monofer® (ferric derisomaltose) would be the first choice parenteral iron for the treatment of iron deficiency at Homerton hospital.

  ferric derisomaltose Hospital only
Monofer® (ferric derisomaltose) for the treatment of iron deficiency anaemia

May 2022 - The Joint Prescribing Group (JPG) agreed to approve the addition of Monofer® as first line parenteral iron for the treatment of iron deficiency at Homerton. 

Formulary status: Blue (hospital only)

  Solution for injection
Diafer (Pharmacosmos UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  ferric maltol Not approved for prescribing
  ferrous fumarate Joint formulary choice
  Oral solution
Ferrous fumarate (Non-proprietary) Joint formulary choice
Galfer (Thornton & Ross Ltd) Joint formulary choice
  ferrous fumarate with folic acid Not approved for prescribing
  ferrous gluconate Not approved for prescribing
  ferrous sulfate Joint formulary choice
  Modified-release tablet
Ferrograd (Teofarma S.r.l.) Not approved for prescribing
  Oral drops
Ferrous sulfate (Non-proprietary) Not approved for prescribing
  ferrous sulfate with ascorbic acid Not approved for prescribing
  Modified-release tablet
Ferrograd C (Teofarma S.r.l.) Not approved for prescribing
  ferrous sulfate with folic acid Not approved for prescribing
  Modified-release tablet
Ferrograd Folic (Teofarma S.r.l.) Not approved for prescribing
  iron dextran Hospital only
  Solution for injection
CosmoFer (Pharmacosmos UK Ltd) Hospital only
  iron sucrose Hospital only
  Solution for injection
Venofer (Imported (United States), Vifor Pharma UK Ltd) Hospital only
  sodium feredetate Joint formulary choice
  Oral solution
Sodium feredetate (Non-proprietary) Joint formulary choice
Sytron (Kyowa Kirin International UK NewCo Ltd) Joint formulary choice
Blood and blood-forming organs / Megaloblastic anaemia
  cyanocobalamin Not approved for prescribing
  folic acid Joint formulary choice
  Oral solution
Folic acid (Non-proprietary) Joint formulary choice
Lexpec (Rosemont Pharmaceuticals Ltd) Joint formulary choice
  hydroxocobalamin Joint formulary choice
  Solution for injection
Hydroxocobalamin (Non-proprietary) Joint formulary choice
Cobalin (Advanz Pharma) Joint formulary choice
Neo-Cytamen (RPH Pharmaceuticals AB) Joint formulary choice
Blood and blood-forming organs / Iron overload
  deferasirox Hospital only
  deferiprone Hospital only
  Oral solution
Ferriprox (Chiesi Ltd) Hospital only
  desferrioxamine mesilate Hospital only
  Powder for solution for injection
Desferrioxamine mesilate (Non-proprietary) Hospital only
Desferal (Novartis Pharmaceuticals UK Ltd) Hospital only
Blood and blood-forming organs / Neutropenia
  filgrastim Hospital only
  Solution for injection
Accofil (Accord-UK Ltd) Hospital only
Neupogen (Amgen Ltd) Hospital only
Neupogen Singleject (Amgen Ltd) Hospital only
Nivestim (Pfizer Ltd) Hospital only
Zarzio (Sandoz Ltd) Hospital only
  lenograstim Hospital only
  Powder and solvent for solution for injection
Granocyte (Chugai Pharma UK Ltd) Hospital only
  lipegfilgrastim Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Lonquex (Teva UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
  pegfilgrastim Non-formulary at HHFT and not suitable for primary care prescribing
  Solution for injection
Neulasta (Amgen Ltd) Non-formulary at HHFT and not suitable for primary care prescribing
Blood and blood-forming organs / Stem cell mobilisation
  plerixafor Not approved for prescribing
  Solution for injection
Mozobil (Sanofi) Not approved for prescribing
Blood and blood-forming organs / Essential thrombocythaemia
  anagrelide [Specialist drug] Hospital only
  hydroxycarbamide Shared care guideline
A formal Shared Care Guideline (SCG) may be available

Happy to prescribe

If you are asked to continue treatment for a specific condition for which a shared care guideline is available and you are happy to prescribe in accordance with the guidance then take over the agreed responsibilities, including prescribing. Please obtain a copy of the SCG from secondary care or via the link below. 

Unhappy to prescribe

If sufficient information has not been provided and if you do not feel happy to continue to prescribe then it is advisable to refer the patient back to the specialist clinic. Please complete an inappropriate request communication form and send this as soon as possible to the contact provided in the form. 

Blood and blood-forming organs / Thrombocytopenias
  avatrombopag Hospital only NICE TA626
NICE TA853
NICE TA626 - Avatrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure (June 2020)

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

NICE TA853 - Avatrombopag for treating primary chronic immune thrombocytopenia (December 2022)

This medicine is recommended for use at Homerton Healthcare NHS Foundation Trust provided it is used specifically in accordance with the NICE Technology Appraisal.

  lusutrombopag Non-formulary at HHFT and not suitable for primary care prescribing NICE TA617
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

Blood and blood-forming organs / Acquired thrombotic thrombocytopenic purpura
  caplacizumab Non-formulary at HHFT and not suitable for primary care prescribing NICE TA667
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  Powder and solvent for solution for injection
Cablivi (Sanofi) Non-formulary at HHFT and not suitable for primary care prescribing
Blood and blood-forming organs / Immune thrombocytopenia
  fostamatinib Non-formulary at HHFT and not suitable for primary care prescribing NICE TA835
Where positive NICE Technology Appraisal(s) apply to this medicine but Homerton Healthcare NHS Foundation Trust does not provide the service

This medicine is not recommended for use at Homerton Healthcare NHS Foundation Trust as the trust does not provide this specialist service. Note that this medicine may be prescribed by other provider trusts that are accredited to provide this specialist service.

  Oral tablet
Tavlesse (Grifols UK Ltd) Non-formulary at HHFT and not suitable for primary care prescribing