| Endocrine system | |||||
|---|---|---|---|---|---|
| Endocrine system / Adrenocortical function testing | |||||
| tetracosactide | On Formulary | ||||
| Solution for injection | |||||
| Synacthen (Atnahs Pharma UK Ltd) | On Formulary | ||||
| Suspension for injection | |||||
| Synacthen Depot (Atnahs Pharma UK Ltd) | Off Formulary | ||||
| Endocrine system / Assessment of pituitary function | |||||
| gonadorelin | Off Formulary | ||||
| Endocrine system / Gonadotrophin replacement therapy | |||||
| choriogonadotropin alfa | Off Formulary | ||||
| Solution for injection | |||||
| Ovitrelle (Merck Serono Ltd) | Off Formulary | ||||
| follitropin alfa | Off Formulary | ||||
| Solution for injection | |||||
| Bemfola (Gedeon Richter (UK) Ltd) | Off Formulary | ||||
| Gonal-f (Merck Serono Ltd) | Off Formulary | ||||
| Ovaleap (Theramex HQ UK Ltd) | Off Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Gonal-f (Merck Serono Ltd) | Off Formulary | ||||
| lutropin alfa | Off Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Luveris (Merck Serono Ltd) | Off Formulary | ||||
| menotrophin | Off Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Menopur (Ferring Pharmaceuticals Ltd) | Off Formulary | ||||
| Meriofert (IBSA Pharma Ltd) | Off Formulary | ||||
| Endocrine system / Growth hormone disorders | |||||
| pegvisomant | Off Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Somavert (Pfizer Ltd) | Off Formulary | ||||
| somatropin | Restricted |
NICE TA64 |
|||
| Solution for injection | |||||
| Norditropin NordiFlex (Novo Nordisk Ltd) | Restricted | ||||
| NutropinAq (Ipsen Ltd) | Restricted | ||||
| Omnitrope SurePal (Sandoz Ltd) | Restricted | ||||
| Saizen (Merck Serono Ltd) | Restricted | ||||
| Powder and solvent for solution for injection | |||||
| Genotropin (Pfizer Ltd) | Restricted | ||||
| Genotropin GoQuick (Pfizer Ltd) | Restricted | ||||
| Genotropin MiniQuick (Pfizer Ltd) | Restricted | ||||
| Humatrope (Eli Lilly and Company Ltd) | Restricted | ||||
| Zomacton (Ferring Pharmaceuticals Ltd) | Restricted | ||||
| Endocrine system / Acromegaly | |||||
| octreotide | Off Formulary | ||||
| Solution for injection | |||||
| Octreotide (Non-proprietary) | Off Formulary | ||||
| Sandostatin (Novartis Pharmaceuticals UK Ltd) | Off Formulary | ||||
| Powder and solvent for suspension for injection | |||||
| Sandostatin LAR (Novartis Pharmaceuticals UK Ltd) | Off Formulary | ||||
| Endocrine system / Diabetes mellitus | |||||
| acarbose | Off Formulary | ||||
| alogliptin | Off Formulary | ||||
| biphasic insulin aspart | On Formulary | ||||
| Suspension for injection | |||||
| NovoMix 30 FlexPen (Novo Nordisk Ltd) | On Formulary | ||||
| NovoMix 30 Penfill (Novo Nordisk Ltd) | On Formulary | ||||
| biphasic insulin lispro | Off Formulary | ||||
| Suspension for injection | |||||
| Humalog Mix25 (Eli Lilly and Company Ltd) | Off Formulary | ||||
| Humalog Mix25 KwikPen (Eli Lilly and Company Ltd) | Off Formulary | ||||
| Humalog Mix50 (Eli Lilly and Company Ltd) | Off Formulary | ||||
| Humalog Mix50 KwikPen (Eli Lilly and Company Ltd) | Off Formulary | ||||
| biphasic isophane insulin | Off Formulary | ||||
| Suspension for injection | |||||
| Humulin M3 (Eli Lilly and Company Ltd) | Off Formulary | ||||
| Humulin M3 KwikPen (Eli Lilly and Company Ltd) | Off Formulary | ||||
| Hypurin Porcine 30/70 Mix (Wockhardt UK Ltd) | Off Formulary | ||||
| canagliflozin | Restricted |
NICE TA390 NICE TA315 |
|||
| dapagliflozin | Restricted |
NICE TA288 NICE TA390 NICE TA418 NICE TA679 NICE TA902 NICE TA775 |
|||
| dapagliflozin with metformin | Restricted | ||||
|
Xigduo®
As per NICE guidance only. |
|||||
| empagliflozin | Restricted |
NICE TA390 NICE TA336 NICE TA773 NICE TA929 NICE TA942 |
|||
| empagliflozin with linagliptin | Off Formulary | ||||
| empagliflozin with metformin | Off Formulary | ||||
| ertugliflozin | Restricted |
NICE TA572 NICE TA583 |
|||
| exenatide | Restricted | ||||
| Solution for injection | |||||
| Byetta (AstraZeneca UK Ltd) | Restricted | ||||
| gliclazide | On Formulary | ||||
| Modified-release tablet | |||||
| Gliclazide (Non-proprietary) | Off Formulary | ||||
| Diamicron MR (Servier Laboratories Ltd) | Off Formulary | ||||
| Edicil MR (Teva UK Ltd) | Off Formulary | ||||
| Ziclaseg (Lupin Healthcare (UK) Ltd) | Off Formulary | ||||
| glimepiride | Off Formulary | ||||
| glipizide | On Formulary | ||||
| insulin | On Formulary |
NICE TA151 NICE TA943 |
|||
| Solution for injection | |||||
| Insulin (Non-proprietary) | On Formulary | ||||
| Actrapid (Novo Nordisk Ltd) | On Formulary | ||||
| Humulin S (Eli Lilly and Company Ltd) | On Formulary | ||||
| Hypurin Porcine Neutral (Wockhardt UK Ltd) | Off Formulary | ||||
| insulin aspart | On Formulary |
NICE TA151 |
|||
| Solution for injection | |||||
| NovoRapid (Novo Nordisk Ltd) | On Formulary | ||||
| NovoRapid FlexPen (Novo Nordisk Ltd) | On Formulary | ||||
| NovoRapid FlexTouch (Novo Nordisk Ltd) | On Formulary | ||||
| NovoRapid Penfill (Novo Nordisk Ltd) | On Formulary | ||||
| NovoRapid PumpCart (Novo Nordisk Ltd) | Off Formulary | ||||
| insulin degludec | Off Formulary | ||||
| Solution for injection | |||||
| Tresiba FlexTouch (Novo Nordisk Ltd) | Off Formulary | ||||
| Tresiba Penfill (Novo Nordisk Ltd) | Off Formulary | ||||
| insulin detemir | On Formulary | ||||
| Solution for injection | |||||
| Levemir FlexPen (Novo Nordisk Ltd) | On Formulary | ||||
| Levemir InnoLet (Novo Nordisk Ltd) | On Formulary | ||||
| Levemir Penfill (Novo Nordisk Ltd) | On Formulary | ||||
| insulin glargine | On Formulary | ||||
| Solution for injection | |||||
| Abasaglar (Eli Lilly and Company Ltd) | On Formulary | ||||
| Abasaglar KwikPen (Eli Lilly and Company Ltd) | On Formulary | ||||
| Toujeo (Sanofi) | On Formulary | ||||
| insulin glulisine | Off Formulary |
NICE TA151 |
|||
| Solution for injection | |||||
| Apidra (Sanofi) | Off Formulary | ||||
| Apidra SoloStar (Sanofi) | Off Formulary | ||||
| insulin lispro | On Formulary |
NICE TA151 |
|||
| Solution for injection | |||||
| Humalog (Eli Lilly and Company Ltd) | On Formulary | ||||
| Humalog KwikPen (Eli Lilly and Company Ltd) | On Formulary | ||||
| isophane insulin | Off Formulary | ||||
| Suspension for injection | |||||
| Humulin I (Eli Lilly and Company Ltd) | On Formulary | ||||
| Humulin I KwikPen (Eli Lilly and Company Ltd) | On Formulary | ||||
| Hypurin Porcine Isophane (Wockhardt UK Ltd) | Off Formulary | ||||
| Insulatard (Novo Nordisk Ltd) | On Formulary | ||||
| Insulatard InnoLet (Novo Nordisk Ltd) | On Formulary | ||||
| Insulatard Penfill (Novo Nordisk Ltd) | On Formulary | ||||
| linagliptin | Off Formulary | ||||
| liraglutide | Restricted |
NICE TA664 |
|||
|
LIRAGLUTIDE
For use in diabetes per NICE guidance only. Not relevant to QVH for managing obesity. |
|||||
| Solution for injection | |||||
| Saxenda (Novo Nordisk Ltd) | Restricted | ||||
|
LIRAGLUTIDE
For use in diabetes per NICE guidance only. Not relevant to QVH for managing obesity. |
|||||
| Victoza (Novo Nordisk Ltd) | Restricted | ||||
|
LIRAGLUTIDE
For use in diabetes per NICE guidance only. Not relevant to QVH for managing obesity. |
|||||
| lixisenatide | Off Formulary | ||||
| Solution for injection | |||||
| Lyxumia (Sanofi) | Off Formulary | ||||
| metformin hydrochloride | On Formulary | ||||
| Modified-release tablet | |||||
| Metformin hydrochloride (Non-proprietary) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Glucient SR (Consilient Health Ltd) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Glucophage SR (Merck Serono Ltd) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Meijumet (Medreich Plc) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Metabet SR (Morningside Healthcare Ltd) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Sukkarto SR (Morningside Healthcare Ltd) | Restricted | ||||
|
Modified release
Modified release only after confirmed intolerance to immediate release preparation |
|||||
| Oral solution | |||||
| Metformin hydrochloride (Non-proprietary) | On Formulary | ||||
| pioglitazone | On Formulary | ||||
| repaglinide | On Formulary | ||||
| saxagliptin | Off Formulary | ||||
| saxagliptin with dapagliflozin | Off Formulary | ||||
| semaglutide | Off Formulary |
NICE TA875 |
|||
| sitagliptin | Restricted | ||||
| sitagliptin with metformin | Off Formulary | ||||
| tolbutamide | Off Formulary | ||||
| vildagliptin | Restricted | ||||
| vildagliptin with metformin | Off Formulary | ||||
| Endocrine system / Diabetic nephropathy | |||||
| captopril | Off Formulary | ||||
| irbesartan | Off Formulary | ||||
| losartan potassium | On Formulary | ||||
| Endocrine system / Diabetes, diagnosis and monitoring | |||||
| glucose | On Formulary | ||||
| Infusion | |||||
| Glucose (Non-proprietary) | On Formulary | ||||
| Solution for infusion | |||||
| Glucose (Non-proprietary) | On Formulary | ||||
| Endocrine system / Diabetic neuropathy | |||||
| capsaicin | On Formulary | ||||
| carbamazepine | |||||
| Modified-release tablet | |||||
| Tegretol Retard (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
| Oral suspension | |||||
| Carbamazepine (Non-proprietary) | On Formulary | ||||
| Tegretol (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
| Suppository | |||||
| Carbamazepine (Non-proprietary) | On Formulary | ||||
| Endocrine system / Hypoglycaemia | |||||
| glucagon | On Formulary | ||||
| Powder and solvent for solution for injection | |||||
| GlucaGen Hypokit (Novo Nordisk Ltd) | On Formulary | ||||
| glucose | On Formulary | ||||
| Infusion | |||||
| Glucose (Non-proprietary) | On Formulary | ||||
| Solution for infusion | |||||
| Glucose (Non-proprietary) | On Formulary | ||||
| Endocrine system / Chronic hypoglycaemia | |||||
| diazoxide | Off Formulary | ||||
| Endocrine system / Corticosteroid responsive conditions | |||||
| betamethasone | On Formulary | ||||
|
Betnovate®
1st Line potent corticosteroid |
|||||
| Solution for injection | |||||
| Betamethasone (Non-proprietary) | Off Formulary | ||||
| deflazacort | Off Formulary | ||||
| dexamethasone | On Formulary |
NICE TA229 NICE TA824 NICE TA460 |
|||
| fludrocortisone acetate | On Formulary | ||||
| hydrocortisone | On Formulary | ||||
|
HYDROCORTISONE
Topical 1st Line mild corticosteroid is Hydrocortisone. Also 1st Line for overgranulation in PAEDS 1% strength.
Softacort eye drops are second line. Restricted to patients that cannot tolerate FML eye drops |
|||||
| methylprednisolone | On Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Solu-Medrone (Pfizer Ltd) | On Formulary | ||||
| Suspension for injection | |||||
| Depo-Medrone (Pfizer Ltd) | On Formulary | ||||
| prednisolone | On Formulary | ||||
| Eye drops | |||||
| Prednisolone (Non-proprietary) | On Formulary | ||||
| triamcinolone acetonide | On Formulary | ||||
| Suspension for injection | |||||
| Adcortyl Intra-articular / Intradermal (Bristol-Myers Squibb Pharmaceuticals Ltd) | On Formulary | ||||
| Kenalog (Bristol-Myers Squibb Pharmaceuticals Ltd) | On Formulary | ||||
| Endocrine system / Cushing's syndrome and disease | |||||
| ketoconazole | Off Formulary | ||||
| metyrapone | Off Formulary | ||||
| pasireotide | Off Formulary | ||||
| Solution for injection | |||||
| Signifor (Recordati Rare Diseases UK Ltd) | Off Formulary | ||||
| Powder and solvent for suspension for injection | |||||
| Signifor (Recordati Rare Diseases UK Ltd) | Off Formulary | ||||
| Endocrine system / Female sex hormone responsive conditions | |||||
| clonidine hydrochloride | Restricted | ||||
|
CLONIDINE HYDROCHLORIDE
In ITU for management of agitation and difficult opioid withdrawal -UNLICENSED indication |
|||||
| conjugated oestrogens (equine) | Off Formulary | ||||
| dienogest | Off Formulary | ||||
| estradiol with dydrogesterone | Off Formulary | ||||
| Form unstated | |||||
| Femoston 1/10 (Viatris UK Healthcare Ltd) | Off Formulary | ||||
| Femoston 2/10 (Viatris UK Healthcare Ltd) | Off Formulary | ||||
| ethinylestradiol | Off Formulary | ||||
| medroxyprogesterone acetate | Off Formulary | ||||
| Suspension for injection | |||||
| Depo-Provera (Pfizer Ltd) | Off Formulary | ||||
| Sayana Press (Pfizer Ltd) | Off Formulary | ||||
| norethisterone | Off Formulary | ||||
| Solution for injection | |||||
| Noristerat (Bayer Plc) | Off Formulary | ||||
| progesterone | Off Formulary | ||||
| Solution for injection | |||||
| Lubion (IBSA Pharma Ltd) | Off Formulary | ||||
| Vaginal gel | |||||
| Crinone (Merck Serono Ltd) | Off Formulary | ||||
| raloxifene hydrochloride | Restricted |
NICE TA160 NICE TA161 |
|||
|
RALOXIFENE HYDROCHLORIDE
Only for secondary prevention of osteoporotic fragility fractures in postmenopausal women if bisphosphonates not tolerated or contraindicated and other NICE criteria met. |
|||||
| tibolone | Off Formulary | ||||
| Endocrine system / Anti-oestrogens | |||||
| clomifene citrate | Off Formulary | ||||
| Endocrine system / Male sex hormone responsive conditions | |||||
| testosterone | Off Formulary | ||||
| Endocrine system / Male sex hormone antagonism | |||||
| cyproterone acetate | Off Formulary | ||||
| Endocrine system / Dopamine responsive conditions | |||||
| bromocriptine | Off Formulary | ||||
| cabergoline | Off Formulary | ||||
| quinagolide | Off Formulary | ||||
| Form unstated | |||||
| Quinagolide (Non-proprietary) | Off Formulary | ||||
| Endocrine system / Bone metabolism disorders | |||||
| alendronic acid | On Formulary |
NICE TA464 |
|||
| Oral solution | |||||
| Alendronic acid (Non-proprietary) | Off Formulary | ||||
| calcitonin (salmon) | Off Formulary | ||||
| Solution for injection | |||||
| Calcitonin (salmon) (Non-proprietary) | Off Formulary | ||||
| calcitriol | Off Formulary | ||||
| Oral solution | |||||
| Calcitriol (Non-proprietary) | Off Formulary | ||||
| denosumab | Restricted |
NICE TA204 NICE TA265 |
|||
| Solution for injection | |||||
| Prolia (Amgen Ltd) | Restricted | ||||
| Xgeva (Amgen Ltd) | Restricted | ||||
| ibandronic acid | Off Formulary |
NICE TA464 |
|||
| Solution for injection | |||||
| Ibandronic acid (Non-proprietary) | Off Formulary | ||||
| Bonviva (Atnahs Pharma UK Ltd) | Off Formulary | ||||
| Solution for infusion | |||||
| Ibandronic acid (Non-proprietary) | Off Formulary | ||||
| Bondronat (Atnahs Pharma UK Ltd) | Off Formulary | ||||
| pamidronate disodium | Off Formulary | ||||
| Solution for infusion | |||||
| Pamidronate disodium (Non-proprietary) | Off Formulary | ||||
| raloxifene hydrochloride | Restricted |
NICE TA160 NICE TA161 |
|||
|
RALOXIFENE HYDROCHLORIDE
Only for secondary prevention of osteoporotic fragility fractures in postmenopausal women if bisphosphonates not tolerated or contraindicated and other NICE criteria met. |
|||||
| risedronate sodium | On Formulary |
NICE TA464 |
|||
| romosozumab | Restricted |
NICE TA791 |
|||
| sodium clodronate | Off Formulary | ||||
| strontium ranelate | Off Formulary | ||||
| teriparatide | Restricted |
NICE TA161 |
|||
| Solution for injection | |||||
| Forsteo (Eli Lilly and Company Ltd) | Restricted | ||||
| zoledronic acid | Off Formulary |
NICE TA464 |
|||
| Infusion | |||||
| Aclasta (Sandoz Ltd) | Off Formulary | ||||
| Zometa (Phoenix Labs Ltd) | Off Formulary | ||||
| Endocrine system / Diabetes insipidus | |||||
| chlortalidone | Off Formulary | ||||
| desmopressin | Restricted | ||||
| Oral lyophilisate | |||||
| DesmoMelt (Ferring Pharmaceuticals Ltd) | Off Formulary | ||||
| Noqdirna (Ferring Pharmaceuticals Ltd) | Off Formulary | ||||
| Spray | |||||
| Desmopressin (Non-proprietary) | Off Formulary | ||||
| Desmospray (Imported (Germany)) | Off Formulary | ||||
| vasopressin | Restricted | ||||
|
Vasopressin
ITU use only |
|||||
| Solution for injection | |||||
| Vasopressin (Non-proprietary) | Restricted | ||||
| Endocrine system / Syndrome of inappropriate antidiuretic hormone secretion | |||||
| tolvaptan | Off Formulary |
NICE TA358 |
|||
| Endocrine system / Thyroid disorders | |||||
| thyrotropin alfa | Off Formulary | ||||
| Powder for solution for injection | |||||
| Thyrogen (Sanofi) | Off Formulary | ||||
| Endocrine system / Hyperthyroidism | |||||
| carbimazole | On Formulary | ||||
| iodide with iodine | Off Formulary | ||||
| metoprolol tartrate | On Formulary | ||||
| Solution for injection | |||||
| Betaloc (Recordati Pharmaceuticals Ltd) | Off Formulary | ||||
| nadolol | Off Formulary | ||||
| propranolol hydrochloride | On Formulary | ||||
| propylthiouracil | Restricted | ||||
| Endocrine system / Hypothyroidism | |||||
| levothyroxine sodium | On Formulary | ||||
| Oral solution | |||||
| Levothyroxine sodium (Non-proprietary) | On Formulary | ||||
| liothyronine sodium | Restricted | ||||
|
Liothyronine
Injection may be used short term post thyroid surgery. Not for initiation in primary care. On-going use only after review by a consultatnt endocrinoligist. See Sussex Formulary for more details |
|||||
| Powder for solution for injection | |||||
| Liothyronine sodium (Non-proprietary) | On Formulary | ||||
| Endocrine system / Gonadotrophin responsive conditions | |||||
| buserelin | Off Formulary | ||||
| Solution for injection | |||||
| Suprecur (Neon Healthcare Ltd) | Off Formulary | ||||
| Suprefact (Neon Healthcare Ltd) | Off Formulary | ||||
| Spray | |||||
| Suprecur (Neon Healthcare Ltd) | Off Formulary | ||||
| cetrorelix | Off Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Cetrotide (Merck Serono Ltd) | Off Formulary | ||||
| ganirelix | Off Formulary | ||||
| goserelin | Off Formulary | ||||
| leuprorelin acetate | Off Formulary | ||||
| Powder and solvent for suspension for injection | |||||
| Prostap 3 DCS (Takeda UK Ltd) | Off Formulary | ||||
| Prostap SR DCS (Takeda UK Ltd) | Off Formulary | ||||
| nafarelin | Off Formulary | ||||
| Spray | |||||
| Synarel (Pfizer Ltd) | Off Formulary | ||||
| triptorelin | Off Formulary | ||||
| Powder and solvent for suspension for injection | |||||
| Decapeptyl SR (Ipsen Ltd) | Off Formulary | ||||
| Gonapeptyl Depot (Ferring Pharmaceuticals Ltd) | Off Formulary | ||||
| Salvacyl (Ipsen Ltd) | Off Formulary | ||||
| Endocrine system / Breast pain (mastalgia) | |||||
| tamoxifen | On Formulary | ||||
|
TAMOXIFEN
Advise to stop 4 weeks before major breast surgery and restart 2 weeks after. |
|||||
| Oral solution | |||||
| Tamoxifen (Non-proprietary) | On Formulary | ||||
|
TAMOXIFEN
Advise to stop 4 weeks before major breast surgery and restart 2 weeks after. |
|||||