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Nervous system
Nervous system / Dystonias and other involuntary movements
  botulinum toxin type A Restricted NICE TA260
NICE TA605
BOTULINUM TOXIN TYPE A

FTG approved for focal spasticity in limbs, migraine, vaginismus, blepharospasm, hemifacial spasm, and anal fissure. All usage in accordance to trust agreed pathways and guidelines.

  Powder for solution for injection
Botox (AbbVie Ltd) Off Formulary
Dysport (Ipsen Ltd) Off Formulary
  chlorpromazine hydrochloride Off Formulary
Chlorpromazine

In psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary and for nausea and labyrinth disorders it is Red.

  clonidine hydrochloride Off Formulary
CLONIDINE HYDROCHLORIDE

Patches - Pain clinic & Injection - ITU/NNU

  clozapine Restricted
CLOZAPINE

Initiation and maintenance by Mental Health team.

This is Red (for hospital prescribing only) in the Black Country IMOG formulary

  diazepam On Formulary
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  haloperidol Off Formulary
  Oral solution
Haldol (Essential Pharma Ltd) Off Formulary
  orphenadrine hydrochloride Off Formulary
  Oral solution
Orphenadrine hydrochloride (Non-proprietary) On Formulary
  pericyazine Off Formulary
Pericyazine

This is AI (can be prescribed in primary care after specialist initiation by the Mental Health team) in the Black Country IMOG formulary.

  piracetam Off Formulary
  pramipexole Restricted
PRAMIPEXOLE

Neurologists and Parkinson's disease. Prescribe generically.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  prochlorperazine On Formulary
Prochlorperazine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Prescribe generically.

  procyclidine hydrochloride On Formulary
  promazine hydrochloride Off Formulary
  ropinirole On Formulary
  rotigotine Restricted
ROTIGOTINE

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  tetrabenazine Restricted
TETRABENAZINE

Consultant Neurologists and Consultant Paediarticians specialising in neuro-disability or epilepsy.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  trifluoperazine Off Formulary
Trifluoperazine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  trihexyphenidyl hydrochloride Restricted
Trihexyphenidyl

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

Nervous system / Parkinson's disease
  amantadine hydrochloride Restricted NICE TA158
NICE TA168
Amantadine

Not regularly stocked in the Trust. This is Red in the Black Country IMOC formulary, i.e. for hospital prescribing only and AI (can be prescribed in primary care after specialist initiation) for Parkinson's disease in the Black Country IMOG formulary.

  apomorphine hydrochloride Restricted
APOMORPHINE HYDROCHLORIDE

Neurologists and Parkinson's disease.

This is AS (is appropriate for shared care) in the Black Country IMOG formulary.

  bromocriptine Off Formulary
BROMOCRIPTINE

Suppression of lactation only.

This is AR in the Black Country IMOC formulary, i.e. may be prescribed in primary care after specialist recommendation.

  cabergoline Off Formulary
CABERGOLINE

Consultant gynaecologists and endocrinology, (it is also allowed for Neurologists and Parkinson's disease second-line noting MHRA guidance - see chapter 4).

This is AR in the Black Country IMOC formulary, i.e. may be prescribed in primary care after specialist recommendation.

  co-beneldopa On Formulary
Co-beneldopa

Prescribe generically.

  co-careldopa On Formulary
Co-careldopa

Prescibe generically. Most brands are non-formulary

  Modified-release tablet
Caramet CR (Teva UK Ltd) Off Formulary
Half Sinemet CR (Organon Pharma (UK) Ltd) Off Formulary
Lecado (Sandoz Ltd) Off Formulary
Sinemet CR (Organon Pharma (UK) Ltd) Off Formulary
  Oral tablet
Sinemet 110 (Organon Pharma (UK) Ltd) Off Formulary
Sinemet 275 (Organon Pharma (UK) Ltd) Off Formulary
Sinemet 62.5 (Organon Pharma (UK) Ltd) Off Formulary
Sinemet Plus (Organon Pharma (UK) Ltd) Off Formulary
  entacapone Restricted
  foslevodopa with foscarbidopa Restricted NICE TA934
Foslevodopa with foscarbidopa

For consultant neurologists only in patient's who meet the criteria in the shared care agreement.

  levodopa with carbidopa and entacapone On Formulary
Levodopa with carbidopa and entacapone

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  opicapone Restricted
Opicapone

Initiation and stabilisation by specialist before transfer to primary care.  Specialist to retain prescribing for minimum of 3 months to establish efficacy/benefit. Second line therapy to entacapone, in patients who fail to respond to, or are intolerant of, entacapone, in situations where apomorphine therapy has been considered. 

  orphenadrine hydrochloride Off Formulary
  Oral solution
Orphenadrine hydrochloride (Non-proprietary) On Formulary
  pramipexole Restricted
PRAMIPEXOLE

Neurologists and Parkinson's disease. Prescribe generically.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  procyclidine hydrochloride On Formulary
  rasagiline Restricted
RASAGILINE

Patients of Dr Clarke and Dr Nicholls for third-line use.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  ropinirole On Formulary
  rotigotine Restricted
ROTIGOTINE

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  safinamide Restricted
Safinamide

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

Third-line use.

  selegiline hydrochloride On Formulary
Selegiline

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  tolcapone Off Formulary
  trihexyphenidyl hydrochloride Restricted
Trihexyphenidyl

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

Nervous system / Alcohol dependence
  acamprosate calcium Restricted
  carbamazepine On Formulary
CARBAMAZEPINE

For psychoses and related disorders this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  Suppository
Carbamazepine (Non-proprietary) Off Formulary
  chlordiazepoxide hydrochloride Restricted
  clomethiazole Off Formulary
  diazepam On Formulary
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  disulfiram Off Formulary
  naltrexone hydrochloride Nice-approved drug NICE TA115
Nervous system / Nicotine dependence
  bupropion hydrochloride On Formulary
  Modified-release tablet
Zyban (GlaxoSmithKline UK Ltd) Off Formulary
  nicotine On Formulary
  Sublingual tablet
Nicotine (Non-proprietary) Off Formulary
  Transdermal patch
Nicotine (Non-proprietary) On Formulary
  Spray
Nicotine (Non-proprietary) Off Formulary
  varenicline Restricted NICE TA123
Nervous system / Opioid dependence
  buprenorphine Restricted NICE TA114
BUPRENORPHINE

This is Red in the Black Country IMOG formulary, i.e for hospital prescribing only, for substance misuse after specialist initiation and maintenance.

The patches are Green for pain.

  Sublingual tablet
Buprenorphine (Non-proprietary) Restricted
Prefibin (Sandoz Ltd) Restricted
Temgesic (Eumedica Pharma Ltd) Off Formulary
  buprenorphine with naloxone Off Formulary
  lofexidine hydrochloride Off Formulary
  methadone hydrochloride Restricted NICE TA114
METHADONE HYDROCHLORIDE

For palliative care methadone is AI in the Black Country IMOC formulary, i.e. for prescribing in primary care after specialist initiation

As per protocol for patients with opioid dependence in accordance with the NICE guidelines and criteria.

  naltrexone hydrochloride Nice-approved drug NICE TA115
Nervous system / Local anaesthesia
  adrenaline with articaine hydrochloride Off Formulary
Adrenaline with articaine

See indiviudal products for formulary status

  Solution for injection
Septanest (Septodont Ltd) Restricted
Septanest

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  bupivacaine hydrochloride Restricted
Bupivacaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only, but Black for use in pain.

  bupivacaine with adrenaline Restricted
Bupivacaine with adrenaline

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only, but Black for use in pain.

  chloroprocaine hydrochloride Restricted
Chloroprocaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  levobupivacaine Restricted
Levobupivacaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  lidocaine hydrochloride Restricted
LIDOCAINE HYDROCHLORIDE

lidocaine 2% with adrenaline 1 in 80,000 is restricted to dental, ENT and local anaesthesia by those experienced.

The 4% cream and 5% ointment ares Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Versatis®

Pain Clinic for neuropathic pain. For post hepatic neuralgia this is Green in the Black Country IMOG formulary.

  Ointment
Lidocaine hydrochloride (Non-proprietary) Restricted
  Spray
Stud 100 (Pound International Ltd) Off Formulary
  Cutaneous cream
LMX 4 (Ferndale Pharmaceuticals Ltd) Restricted
Vagisil medicated (Combe International Ltd) Off Formulary
  lidocaine with cetrimide Off Formulary
  lidocaine with phenylephrine Off Formulary
  lidocaine with prilocaine Off Formulary
  Cutaneous cream
Emla (Aspen Pharma Trading Ltd) On Formulary
Nulbia (Glenmark Pharmaceuticals Europe Ltd) Off Formulary
  mepivacaine hydrochloride Restricted
Mepivacaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  mepivacaine with adrenaline Off Formulary
  prilocaine hydrochloride Restricted
PRILOCAINE HYDROCHLORIDE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  prilocaine with felypressin Off Formulary
  ropivacaine hydrochloride Restricted
ROPIVACAINE HYDROCHLORIDE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

The 400mg in 200ml infusion is restricted to the Enhanced Recevery protocol only

  tetracaine On Formulary
TETRACAINE

This is Red in the Black Country formulary, i.e. for hospital prescribing only.

  Cutaneous gel
Ametop (Alliance Pharmaceuticals Ltd) On Formulary
Nervous system / Dementia
  donepezil hydrochloride Restricted NICE TA217
DONEPEZIL HYDROCHLORIDE

Donepezil has the lowest acquistion costs and should be used first-line for continuation of treatment.

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

  galantamine Restricted NICE TA217
GALANTAMINE

Donepezil has the lowest acquistion costs and should be used first-line.
Galantamine can be continued in patients who are stable on it.

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

  memantine hydrochloride Restricted NICE TA217
MEMANTINE HYDROCHLORIDE

Donepezil has the lowest acquistion costs and should be used first-line
Memantine can be continued in patients who are stable on it.

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

  risperidone On Formulary
RISPERIDONE

Acute mania, add-on therapy for patients who have not responded adequately to SSRIs in obsessive-compulsive disorder, and schizophrenia according to NICE guidelines.

For use in psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

The oral solution is second-line and the orodispersible tablet third-line.

  rivastigmine Restricted NICE TA217
RIVASTIGMINE

Donepezil has the lowest acquistion costs and should be used first-line
The capsules can be continued in patients stable on the drug

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

  Transdermal patch
Exelon (Novartis Pharmaceuticals UK Ltd) Off Formulary
Nervous system / Nausea and labyrinth disorders
  aprepitant Restricted
APREPITANT

Second-line agent in patients who have failed with 5HT3 antagonists.

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  chlorpromazine hydrochloride Restricted
Chlorpromazine

In psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary and for nausea and labyrinth disorders it is Red.

  cinnarizine On Formulary
  cinnarizine with dimenhydrinate Off Formulary
  cyclizine On Formulary
Cyclizine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  domperidone On Formulary
  doxylamine with pyridoxine Off Formulary
  droperidol Off Formulary
  fosaprepitant Restricted
Fosaprepitant

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  granisetron Restricted
GRANISETRON

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  haloperidol On Formulary
  Oral solution
Haldol (Essential Pharma Ltd) Off Formulary
  hyoscine hydrobromide On Formulary
  Solution for injection
Hyoscine hydrobromide (Non-proprietary) On Formulary
  levomepromazine On Formulary
LEVOMEPROMAZINE

Palliative care use only.

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  lorazepam Off Formulary
Lorazepam

For peri-operative use the injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  metoclopramide hydrochloride On Formulary
Metoclopramide

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  nabilone Off Formulary
  ondansetron Restricted
ONDANSETRON

Second line treatment - after antihistamines have been tried. Prescribe generically.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  palonosetron Off Formulary
  palonosetron with netupitant Off Formulary
  prochlorperazine On Formulary
Prochlorperazine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Prescribe generically.

  promethazine hydrochloride On Formulary
Promethazine

Suitable for self-care/purchase, if appropriate, for short term use for insomnia, urticaria, allergies, and travel sickness.

  Oral tablet
Sominex (Dexcel-Pharma Ltd) Off Formulary
  promethazine teoclate Off Formulary
  trifluoperazine Off Formulary
Trifluoperazine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

Nervous system / Ménière's disease
  betahistine dihydrochloride On Formulary
  Oral tablet
Serc (Viatris UK Healthcare Ltd) Off Formulary
Nervous system / Pain
  alfentanil Restricted
ALFENTANIL

The 5mg in 10ml  and 1mg in 2ml strengths are restricted to Theatres.

This is Red (hospital prescribing only) in the Black Country IMOC formulary for per-operative analgesia, and AR (can be prescribed in primary care after specialist recommendation) for pain relief in palliative care patients with advanced renal disease.

  Solution for injection
Rapifen (Piramal Critical Care Ltd) Off Formulary
  aspirin On Formulary
ASPIRIN

Dispersible tablets and suppositories for use in the Trust only.

Enteric coated tablets are for second-line use and for blister packs.

Gastro-resistant tablets are available for the PGD for patients at moderate or high risk of pre-eclampsia ONLY

  Gastro-resistant tablet
Nu-Seals (Alliance Pharmaceuticals Ltd) Off Formulary
  Suppository
Aspirin (Non-proprietary) Off Formulary
  bupivacaine hydrochloride Off Formulary
Bupivacaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only, but Black for use in pain.

  bupivacaine with adrenaline Off Formulary
Bupivacaine with adrenaline

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only, but Black for use in pain.

  bupivacaine with fentanyl Restricted
Bupivacaine with fentanyl

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  buprenorphine Restricted NICE TA114
BUPRENORPHINE

This is Red in the Black Country IMOG formulary, i.e for hospital prescribing only, for substance misuse after specialist initiation and maintenance.

The patches are Green for pain.

  Sublingual tablet
Buprenorphine (Non-proprietary) Off Formulary
Prefibin (Sandoz Ltd) Off Formulary
Temgesic (Eumedica Pharma Ltd) Off Formulary
  Transdermal patch
BuTrans (Napp Pharmaceuticals Ltd) On Formulary
  co-codamol On Formulary
CO-CODAMOL

The 15/300 tablets are first line. The 8/300 tablets are oral solution are Black in the Black Country IMOG formulary.

The effervescent tablets are restricted to patients with swallowing difficulties.

The capsules are 2nd line - only to be considered for patients unable to swallow tablets and where salt content with effervescent formulation would not be favourable for those patients requiring good blood pressure control.

 

  Effervescent tablet
Co-codamol (Non-proprietary) Restricted
  Oral capsule
Co-codamol (Non-proprietary) Restricted
  codeine phosphate Restricted
CODEINE PHOSPHATE

The injection is restricted to A&E, ITU only and is Red in the Black Country IMOG formulary.

Codeine is now contraindicated in children under the age of 12.

See MHRA advice here

  Oral solution
Codeine phosphate (Non-proprietary) On Formulary
Galcodine (Thornton & Ross Ltd) Off Formulary
  diamorphine hydrochloride On Formulary
  Powder for solution for injection
Diamorphine hydrochloride (Non-proprietary) On Formulary
  diclofenac potassium Off Formulary
  dihydrocodeine tartrate On Formulary
Dihydrocodeine

Please prescribe generically, branded products are Black in the Black Country IMOG formulary

  dihydrocodeine with paracetamol On Formulary
  Oral tablet
Dihydrocodeine with paracetamol (Non-proprietary) On Formulary
Remedeine (Crescent Pharma Ltd) Off Formulary
  dipipanone hydrochloride with cyclizine Off Formulary
  esketamine Off Formulary NICE TA854
  fentanyl Restricted
FENTANYL

Theatres, ITU, Pain team and Consultants in palliative care.

The injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

For use in pain products are restricted to Palliative Care specialists and are AR. Fencino and Mezolar Matrix are the preferred brands of patches.

The lozenges and spray are Black and non-formulary.

  Solution for injection
Fentanyl (Non-proprietary) Restricted
Sublimaze (Piramal Critical Care Ltd) Off Formulary
  Transdermal patch
Victanyl (Accord-UK Ltd) Off Formulary
Yemex (Sandoz Ltd) Off Formulary
  hydromorphone hydrochloride Restricted
HYDROMORPHONE HYDROCHLORIDE

This is Black for pain but AR for cancer pain and palliative care.

  ibuprofen On Formulary
IBUPROFEN

Please prescribe generically. The injection and any use for dysmenorrhoea is Red in the Black Country IMOG formulary, i.e. for hospital prescribing only.

  Orodispersible tablet
Nurofen Meltlets (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Modified-release tablet
Brufen Retard (Viatris UK Healthcare Ltd) Off Formulary
  Chewable capsule
Nurofen (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Effervescent granules
Brufen (Viatris UK Healthcare Ltd) Off Formulary
  Oral suspension
Nurofen (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Oral tablet
Brufen (Viatris UK Healthcare Ltd) Off Formulary
Feminax Express (Bayer Plc) Off Formulary
Nurofen Migraine Pain (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Oral capsule
Nurofen Express (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Cutaneous gel
Ibuprofen (Non-proprietary) On Formulary
  levobupivacaine Restricted
Levobupivacaine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  levomepromazine Restricted
LEVOMEPROMAZINE

Palliative care use only.

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  mefenamic acid Off Formulary
MEFENAMIC ACID

Gynaecology for dysmennorhoea only. Please prescribe generically, all branded products, tablets and oral suspension are Black in the Black Country IMOG formulary.

  Oral capsule
Mefenamic acid (Non-proprietary) Off Formulary
  meptazinol Off Formulary
  methadone hydrochloride Restricted NICE TA114
METHADONE HYDROCHLORIDE

For palliative care methadone is AI in the Black Country IMOC formulary, i.e. for prescribing in primary care after specialist initiation

As per protocol for patients with opioid dependence in accordance with the NICE guidelines and criteria.

  methoxyflurane Restricted
Methoxyflurane

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  morphine On Formulary
Morphine

XL formulations only to be used when twice daily MR prearations are not suitable and ONCE daily preparation is required. XL more expensive.

  Modified-release tablet
MST Continus (Napp Pharmaceuticals Ltd) On Formulary
Morphgesic SR (Advanz Pharma) Off Formulary
  Modified-release capsule
MXL (Napp Pharmaceuticals Ltd) Off Formulary
Zomorph (Ethypharm UK Ltd) On Formulary
  Oral solution
Morphine (Non-proprietary) On Formulary
Morhine oral solution

For palliative care the 20 mg/ml preparation is AR in the Black Country formulary

Oramorph (Glenwood GmbH) Off Formulary
  nefopam hydrochloride Off Formulary
  nitrous oxide Restricted
NITROUS OXIDE

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  oxycodone hydrochloride Restricted
OXYCODONE HYDROCHLORIDE

For use in palliative care this is AR in the Black Country IMOC formulary, i.e can be prescribed in primary care after specialist recommendation. Check preferred brands.

See MHRA Drug Safety Update

  Modified-release tablet
Oxylan (G.L. Pharma UK Ltd) Restricted
Oxypro (Ridge Pharma Ltd) Restricted
  Oral capsule
Lynlor (Accord-UK Ltd) Restricted
Shortec (Qdem Pharmaceuticals Ltd) Restricted
  oxycodone with naloxone Off Formulary
  paracetamol On Formulary
PARACETAMOL

Suppositories should be used when the oral route is not available or suitable.

The infusion is restricted to patients who are unable to take oral medications and is Red (for hospital prescribing only) in the Black Country IMOG formulary.

N.B. There have been cases of accidental overdosing with IV paracetamol. Please ensure that your dose is appropriate for the weight of your patient.

The British National Formulary (BNF) suggests caution in patients with hepatocellular insufficiency, chronic alcoholism, chronic malnutrition or dehydration, and to administer a maximum daily infusion dose of 3 g in adults in these patient groups.

In patients who have exceeded a maximum daily dose of 60 mg/kg please discuss urgently with the Clinical Toxicology team or National Poisons Information Service (NPIS).

 

  Orodispersible tablet
Calpol Fastmelts (McNeil Products Ltd) Off Formulary
  Solution for infusion
Paracetamol (Non-proprietary) Restricted
  pentazocine Off Formulary
  pethidine hydrochloride Restricted
Pethidine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  ropivacaine hydrochloride Restricted
ROPIVACAINE HYDROCHLORIDE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

The 400mg in 200ml infusion is restricted to the Enhanced Recevery protocol only

  tapentadol Off Formulary
  tramadol hydrochloride Restricted
TRAMADOL HYDROCHLORIDE

Rheumatology consultants and Pain team (see also acute pain guidelines).

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  tramadol with paracetamol Off Formulary
Nervous system / Headache
  clonidine hydrochloride Restricted
CLONIDINE HYDROCHLORIDE

Patches - Pain clinic & Injection - ITU/NNU

  pizotifen On Formulary
  sumatriptan On Formulary
SUMATRIPTAN

Please prescribe generically.

  Solution for injection
Imigran Subject (GlaxoSmithKline UK Ltd) Off Formulary
  Spray
Imigran (GlaxoSmithKline UK Ltd) On Formulary
  Oral tablet
Imigran (GlaxoSmithKline UK Ltd) Off Formulary
  verapamil hydrochloride Restricted
Verapamil

Tablets are AR (can be prescribed in primary care after specilaist recommendation) for cluster headaches only in the Black Country IMOG formulary.

  Modified-release tablet
Half Securon (Viatris UK Healthcare Ltd) Off Formulary
Securon SR (Viatris UK Healthcare Ltd) Off Formulary
Verapress MR (Dexcel-Pharma Ltd) Off Formulary
  Solution for injection
Securon (Viatris UK Healthcare Ltd) Off Formulary
Nervous system / Migraine
  almotriptan Off Formulary
  amitriptyline hydrochloride On Formulary
  aspirin with metoclopramide Off Formulary
  atenolol Off Formulary
  botulinum toxin type A Restricted NICE TA260
NICE TA605
BOTULINUM TOXIN TYPE A

FTG approved for focal spasticity in limbs, migraine, vaginismus, blepharospasm, hemifacial spasm, and anal fissure. All usage in accordance to trust agreed pathways and guidelines.

  Powder for solution for injection
Botox (AbbVie Ltd) Off Formulary
Dysport (Ipsen Ltd) Off Formulary
  candesartan cilexetil Restricted
  clonidine hydrochloride Off Formulary
CLONIDINE HYDROCHLORIDE

Patches - Pain clinic & Injection - ITU/NNU

  cyclizine On Formulary
Cyclizine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  diclofenac potassium Off Formulary
  eletriptan Off Formulary
  erenumab Restricted NICE TA682
Erenumab

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Blueteq form must be completed where available for this drug and required indication. Please contact the Pharmacy High Cost Drug team if any support needed.

https://www.blueteq-secure.co.uk/Trust/default.aspx

  fremanezumab Restricted NICE TA764
Fremanezumab

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Second-line for patients who have failed oral treatments

  frovatriptan Off Formulary
  galcanezumab Restricted NICE TA659
Galcanezumab

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  metoclopramide hydrochloride On Formulary
Metoclopramide

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  metoprolol tartrate Off Formulary
  Solution for injection
Betaloc (Recordati Pharmaceuticals Ltd) Restricted
Metoprolol injection

The injection is Red in the Black Country IMOG formulary, i.e. for hospital prescribing only.

  nadolol Off Formulary
  naratriptan Off Formulary
  paracetamol with buclizine hydrochloride and codeine phosphate On Formulary
  pizotifen On Formulary
  prochlorperazine On Formulary
Prochlorperazine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Prescribe generically.

  rizatriptan On Formulary
  sodium valproate Off Formulary
SODIUM VALPROATE

See MHRA guidance on prescribing 

https://www.gov.uk/guidance/valproate-use-by-women-and-girls

 

This is AR (can be prescribed in primary care after specialist recommendation) in men and women of non-childbearing potential in the Black Country IMOG formulary.

This is AS (is suitable for shared care) for use in women of childbearing potential and girls.

This is Red (for hospital prescribing only) in pregnancy, in women planning pregnancy an in women of childbearing potential where PREVENT applies, who decline or are unable to use effective contraception.

  sumatriptan On Formulary
SUMATRIPTAN

Please prescribe generically.

  Solution for injection
Imigran Subject (GlaxoSmithKline UK Ltd) Off Formulary
  Spray
Imigran (GlaxoSmithKline UK Ltd) On Formulary
  Oral tablet
Imigran (GlaxoSmithKline UK Ltd) Off Formulary
  timolol maleate Off Formulary
Timolol

This is AR in the Black Country formulary, i.e. may be prescribed in primary care after specialist recommendation.

  tolfenamic acid Off Formulary
  topiramate Restricted
TOPIRAMATE

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability or epilepsy.

For use in migraine this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  trifluoperazine Off Formulary
Trifluoperazine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  valproic acid Off Formulary
VALPROIC ACID

Drug Safety Update January 2015

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  zolmitriptan On Formulary
Nervous system / Neuropathic pain
  amantadine hydrochloride Off Formulary NICE TA158
NICE TA168
Amantadine

Not regularly stocked in the Trust. This is Red in the Black Country IMOC formulary, i.e. for hospital prescribing only and AI (can be prescribed in primary care after specialist initiation) for Parkinson's disease in the Black Country IMOG formulary.

  amitriptyline hydrochloride On Formulary
  capsaicin Restricted
Capsaicin

Qutenza is Red in the Black Country IMOC formulary, i.e. for hospital prescribing only.

Please prescribe by brand.

  Cutaneous patch
Qutenza (Grunenthal Ltd) Restricted
Capsaicin

Qutenza is restricted to the Pain Team only and is also Red in the Black Country IMOC formulary, i.e. for hospital prescribing only.

  Cutaneous cream
Capsaicin (Non-proprietary) On Formulary
  carbamazepine On Formulary
CARBAMAZEPINE

For psychoses and related disorders this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  Suppository
Carbamazepine (Non-proprietary) Off Formulary
  gabapentin On Formulary
Gabapentin

Please see January 2026 MHRA Drug Safety Update regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs.

Gabapentin

The oral solution is for second-line use.

  nortriptyline On Formulary
Nortriptyline

The oral solution is Black in the Black Country IMOG formulary for neuropathic pain but allowed for hospital use as an antidepressant.

  oxycodone hydrochloride Off Formulary
OXYCODONE HYDROCHLORIDE

For use in palliative care this is AR in the Black Country IMOC formulary, i.e can be prescribed in primary care after specialist recommendation. Check preferred brands.

See MHRA Drug Safety Update

  phenytoin Off Formulary
Phenytoin

The solution for injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  pregabalin Restricted
Pregabalin

Please see January 2026 MHRA Drug Safety Update regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs.

PREGABALIN

Pain Clinic, otherwise for continuation of treatment.

For neuropathic pain the capsules are first-line and oral solution second-line.

Nervous system / General anaesthesia
  desflurane Off Formulary
  etomidate Restricted
ETOMIDATE

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Theatres only.

  Emulsion for injection
Etomidate (Non-proprietary) Restricted
  isoflurane Restricted
ISOFLURANE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  nitrous oxide Restricted
NITROUS OXIDE

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  propofol Restricted
PROPOFOL

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically.

  Emulsion for injection
Propofol (Non-proprietary) Restricted
  sevoflurane Restricted
SEVOFLURANE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  thiopental sodium Restricted
THIOPENTAL SODIUM

Theatres, ITU, A&E.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Powder for solution for injection
Thiopental sodium (Non-proprietary) Restricted
Nervous system / CNS and respiratory depression
  naloxone hydrochloride Restricted
Naloxone

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically, the branded products are non-formulary.

  Solution for injection
Prenoxad (Martindale Pharmaceuticals Ltd) Off Formulary
  Spray
Nyxoid (Napp Pharmaceuticals Ltd) Off Formulary
Nervous system / Malignant hyperthermia
  dantrolene sodium Restricted
DANTROLENE SODIUM

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically

Nervous system / Anaesthesia adjuvants
  atropine sulfate On Formulary
  Solution for injection
Atropine sulfate (Non-proprietary) Restricted
Atropine sulfate

This is Red in the Black Country IMOG formulary, i.e. for hospital prescribing only.

  glycopyrronium bromide Restricted
Nervous system / Neuromuscular blockade
  atracurium besilate Restricted
ATRACURIUM BESILATE

Theatres, ITU, NNU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Solution for injection
Atracurium besilate (Non-proprietary) Restricted
  cisatracurium Off Formulary
  mivacurium Restricted
MIVACURIUM

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  pancuronium bromide Restricted
PANCURONIUM BROMIDE

NNU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  rocuronium bromide Restricted
ROCURONIUM BROMIDE

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  suxamethonium chloride Restricted
SUXAMETHONIUM CHLORIDE

Theatres, ITU, ED.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Solution for injection
Suxamethonium chloride (Non-proprietary) Restricted
  vecuronium bromide Restricted
VECURONIUM BROMIDE

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Nervous system / Peri-operative sedation
  alimemazine tartrate Restricted
Alimemazine

For perioperative sedation only this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Oral solution
Alimemazine tartrate (Non-proprietary) Off Formulary
  dexmedetomidine Restricted
DEXMEDETOMIDINE

Use of dexmedetomidineis restricted to Critical Care consultants according to the published guidelines.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  diazepam Restricted
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  ketamine Restricted
KETAMINE

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

10mg/ ml - Neonates, for caudal anaesthesia in paediatrics by those experienced ---
50mg/ ml - Theatres, ITU, A&E, pain team

  Solution for injection
Ketalar (Pfizer Ltd) Restricted
  lorazepam Restricted
Lorazepam

For peri-operative use the injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Solution for injection
Lorazepam (Non-proprietary) Restricted
  midazolam Restricted
MIDAZOLAM

The 50mg in 50ml and 10mg in 5ml strengths are restricted to ITU.

The 10mg in 2ml is restricted to palliative care for the indication of catastrophic bleed, or stridor in community, and seizures.

For status epilepticus prescribe as Buccolam brand.

MIDAZOLAM

Buccal product for use in status epilepticus for patients attending school.

Please prescribe generically.

  propofol Restricted
PROPOFOL

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically.

  Emulsion for injection
Propofol (Non-proprietary) Restricted
  remifentanil Restricted
REMIFENTANIL

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically.

N.B. only the 1mg preparation is stocked for theatres; 5mg vials strictly for ITU use only

  remimazolam Off Formulary
  temazepam Restricted
Temazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Nervous system / Neuromuscular blockade reversal
  neostigmine Restricted
NEOSTIGMINE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  neostigmine with glycopyrronium bromide Restricted
NEOSTIGMINE WITH GLYCOPYRRONIUM BROMIDE

Theatres.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Solution for injection
Neostigmine with glycopyrronium bromide (Non-proprietary) Restricted
  sugammadex Restricted
SUGAMMADEX

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Nervous system / Peri-operative analgesia
  alfentanil Restricted
ALFENTANIL

The 5mg in 10ml  and 1mg in 2ml strengths are restricted to Theatres.

This is Red (hospital prescribing only) in the Black Country IMOC formulary for per-operative analgesia, and AR (can be prescribed in primary care after specialist recommendation) for pain relief in palliative care patients with advanced renal disease.

  Solution for injection
Rapifen (Piramal Critical Care Ltd) Off Formulary
  bupivacaine with fentanyl Restricted
Bupivacaine with fentanyl

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  buprenorphine Restricted NICE TA114
BUPRENORPHINE

This is Red in the Black Country IMOG formulary, i.e for hospital prescribing only, for substance misuse after specialist initiation and maintenance.

The patches are Green for pain.

  Sublingual tablet
Buprenorphine (Non-proprietary) Off Formulary
Prefibin (Sandoz Ltd) Off Formulary
Temgesic (Eumedica Pharma Ltd) Off Formulary
  diclofenac potassium Off Formulary
  esketamine Off Formulary NICE TA854
  Spray
Spravato (Janssen-Cilag Ltd) Off Formulary
  fentanyl Restricted
FENTANYL

Theatres, ITU, Pain team and Consultants in palliative care.

The injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

For use in pain products are restricted to Palliative Care specialists and are AR. Fencino and Mezolar Matrix are the preferred brands of patches.

The lozenges and spray are Black and non-formulary.

  Solution for injection
Fentanyl (Non-proprietary) Restricted
Sublimaze (Piramal Critical Care Ltd) Off Formulary
  Transdermal patch
Victanyl (Accord-UK Ltd) Off Formulary
Yemex (Sandoz Ltd) Off Formulary
  flurbiprofen Restricted
  ibuprofen Restricted
IBUPROFEN

Please prescribe generically. The injection and any use for dysmenorrhoea is Red in the Black Country IMOG formulary, i.e. for hospital prescribing only.

  Orodispersible tablet
Nurofen Meltlets (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Modified-release tablet
Brufen Retard (Viatris UK Healthcare Ltd) Off Formulary
  Chewable capsule
Nurofen (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Effervescent granules
Brufen (Viatris UK Healthcare Ltd) Off Formulary
  Oral suspension
Nurofen (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Oral tablet
Brufen (Viatris UK Healthcare Ltd) Off Formulary
Feminax Express (Bayer Plc) Off Formulary
Nurofen Migraine Pain (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Oral capsule
Nurofen Express (Reckitt Benckiser Healthcare (UK) Ltd) Off Formulary
  Cutaneous gel
Ibuprofen (Non-proprietary) On Formulary
  ketorolac trometamol Restricted
KETOROLAC TROMETAMOL

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

30mg in 1ml only - Theatre recovery, ITU

  Solution for injection
Ketorolac trometamol (Non-proprietary) Restricted
Toradol (Atnahs Pharma UK Ltd) Off Formulary
  Eye drops
Ketorolac trometamol (Non-proprietary) Restricted
Ketorolac eye drops

This is AR in the Black Country formulary, i.e. can be prescribed in primary care after specialist recommendation.

Acular (AbbVie Ltd) On Formulary
  mefenamic acid Off Formulary
MEFENAMIC ACID

Gynaecology for dysmennorhoea only. Please prescribe generically, all branded products, tablets and oral suspension are Black in the Black Country IMOG formulary.

  Oral capsule
Mefenamic acid (Non-proprietary) Off Formulary
  meptazinol Off Formulary
  oxycodone hydrochloride Restricted
OXYCODONE HYDROCHLORIDE

For use in palliative care this is AR in the Black Country IMOC formulary, i.e can be prescribed in primary care after specialist recommendation. Check preferred brands.

See MHRA Drug Safety Update

  Modified-release tablet
Oxylan (G.L. Pharma UK Ltd) Restricted
Oxypro (Ridge Pharma Ltd) Restricted
  Oral capsule
Lynlor (Accord-UK Ltd) Restricted
Shortec (Qdem Pharmaceuticals Ltd) Restricted
  oxycodone with naloxone Off Formulary
  parecoxib Restricted
Parecoxib

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  pethidine hydrochloride Restricted
Pethidine

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  remifentanil Restricted
REMIFENTANIL

Theatres, ITU.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

Please prescribe generically.

N.B. only the 1mg preparation is stocked for theatres; 5mg vials strictly for ITU use only

Nervous system / Reversal of benzodiazepines
  flumazenil On Formulary
Flumazenil

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Solution for injection
Flumazenil (Non-proprietary) On Formulary
Nervous system / Epilepsy and other seizure disorders
  acetazolamide Off Formulary
Acetazolamide

This is Black for high-altitude sickness and Red (for hospital prescribing only) for epilepsy in the Black Country IMOG formulary. 

For ophthalmological indications the injection is Red and oral formulations are AR

  Powder for solution for injection
Diamox (Advanz Pharma) Off Formulary
  brivaracetam Restricted
Brivaracetam

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary except the injection is Red (for hospital prescribing only) 

  cannabidiol Restricted NICE TA614
NICE TA615
NICE TA873
Cannabidiol

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

This is commssioned by NHSE for the indications below and a Blueteq form must be completed before prescribing. Please contact the Pharmacy High-Cost Drugs team if any assistance is required.

Any other use is non-formulary and the non-formulary request process should be followed. 

Adjuvant treatment of seizures associated with Dravet syndrome or Lennox-Gastaut syndrome

  carbamazepine On Formulary
CARBAMAZEPINE

For psychoses and related disorders this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  Suppository
Carbamazepine (Non-proprietary) Off Formulary
  cenobamate Restricted NICE TA753
Cenobamate

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  clobazam Restricted
CLOBAZAM

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability or epilepsy.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  clonazepam Restricted
  eslicarbazepine acetate Restricted
Eslicarbazepine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  ethosuximide Restricted
ETHOSUXIMIDE

To be initiated by consultant paediatricians with epilepsy interest/consultant neurologists. Prescribe the most cost-effective brand in primary care.

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

 

 

  Oral solution
Ethosuximide (Non-proprietary) Restricted
  fenfluramine Restricted NICE TA808
NICE TA1050
Fenfluramine

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

This is commssioned by NHSE for the indications below and a Blueteq form must be completed before prescribing. Please contact the Pharmacy High-Cost Drugs team if any assistance is required.

Dravet syndrome

  fosphenytoin sodium Off Formulary
  gabapentin On Formulary
Gabapentin

Please see January 2026 MHRA Drug Safety Update regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs.

Gabapentin

The oral solution is for second-line use.

  lacosamide Restricted
Lacosamide

Only the solution for infusion is formulary and Red (for hospital prescribing only) in the Black Country IMOG formulary.

  Oral solution
Lacosamide (Non-proprietary) Off Formulary
Vimpat (UCB Pharma Ltd) Off Formulary
  Solution for infusion
Lacosamide (Non-proprietary) Restricted
Vimpat (UCB Pharma Ltd) Restricted
  Oral tablet
Lacosamide (Non-proprietary) Off Formulary
Vimpat (UCB Pharma Ltd) Off Formulary
  lamotrigine On Formulary
Lamotrigine

Third-line use. Prescribe generically. This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary

 

 

  levetiracetam Restricted
LEVETIRACETAM

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability or epilepsy.

Prescribe generically. The solution for infusion is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  magnesium sulfate On Formulary
Magnesium sulfate

TFor prevention of seizures this is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  Solution for injection
Magnesium sulfate (Non-proprietary) On Formulary
  oxcarbazepine Restricted
OXCARBAZEPINE

Neurology.

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  perampanel Restricted
PERAMPANEL

Consultant Neurologists or Associate Specialists in Neurology for third- or fourth-line use in accordance with a RICaD.

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  phenobarbital On Formulary
PHENOBARBITAL

The oral solution is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary but the solution for injection is Red.

  phenytoin On Formulary
Phenytoin

The solution for injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  pregabalin Restricted
Pregabalin

Please see January 2026 MHRA Drug Safety Update regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs.

PREGABALIN

Pain Clinic, otherwise for continuation of treatment.

For neuropathic pain the capsules are first-line and oral solution second-line.

  primidone Restricted
PRIMIDONE

Neurologists and in movement disorder.

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  rufinamide Restricted
Rufinamide

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  sodium valproate On Formulary
SODIUM VALPROATE

See MHRA guidance on prescribing 

https://www.gov.uk/guidance/valproate-use-by-women-and-girls

 

This is AR (can be prescribed in primary care after specialist recommendation) in men and women of non-childbearing potential in the Black Country IMOG formulary.

This is AS (is suitable for shared care) for use in women of childbearing potential and girls.

This is Red (for hospital prescribing only) in pregnancy, in women planning pregnancy an in women of childbearing potential where PREVENT applies, who decline or are unable to use effective contraception.

  stiripentol Off Formulary
  tiagabine Off Formulary
  topiramate Restricted
TOPIRAMATE

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability or epilepsy.

For use in migraine this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  vigabatrin Restricted
VIGABATRIN

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability or epilepsy.

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  zonisamide Restricted
ZONISAMIDE

Consultant Neurologists or Associate Specialists in Neurology for third- or fourth-line use in accordance with an ESCA

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

Nervous system / Status epilepticus
  diazepam On Formulary
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  fosphenytoin sodium Off Formulary
  levetiracetam On Formulary
  lorazepam On Formulary
Lorazepam

For peri-operative use the injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  midazolam Restricted
MIDAZOLAM

The 50mg in 50ml and 10mg in 5ml strengths are restricted to ITU.

The 10mg in 2ml is restricted to palliative care for the indication of catastrophic bleed, or stridor in community, and seizures.

For status epilepticus prescribe as Buccolam brand.

MIDAZOLAM

Buccal product for use in status epilepticus for patients attending school.

Please prescribe generically.

  phenobarbital On Formulary
PHENOBARBITAL

The oral solution is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary but the solution for injection is Red.

  phenytoin On Formulary
Phenytoin

The solution for injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  thiopental sodium Off Formulary
THIOPENTAL SODIUM

Theatres, ITU, A&E.

This is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  Powder for solution for injection
Thiopental sodium (Non-proprietary) Restricted
Nervous system / Anxiety
  alprazolam Off Formulary
  buspirone hydrochloride Restricted
Buspirone

This is AI (can be prescribed in primary care after specialist initiation by a Mental Health Specialist) in the Black Country IMOG formulary.

  chlordiazepoxide hydrochloride Off Formulary
  diazepam On Formulary
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  duloxetine On Formulary
DULOXETINE

Prescribe generically.

For urinary uses the 40 mg strength is the only product available.

 

  escitalopram Restricted
ESCITALOPRAM

Second- or third-line use in anxiety. Prescibe generically.

  lorazepam On Formulary
Lorazepam

For peri-operative use the injection is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  moclobemide Restricted
MOCLOBEMIDE

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  oxazepam Off Formulary
  paroxetine On Formulary
PAROXETINE

In liver impairment or third-line.

  pericyazine Off Formulary
Pericyazine

This is AI (can be prescribed in primary care after specialist initiation by the Mental Health team) in the Black Country IMOG formulary.

  pregabalin Restricted
Pregabalin

Please see January 2026 MHRA Drug Safety Update regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs.

PREGABALIN

Pain Clinic, otherwise for continuation of treatment.

For neuropathic pain the capsules are first-line and oral solution second-line.

  trazodone hydrochloride On Formulary
Trazodone

Prescribe generically.

  trifluoperazine Restricted
Trifluoperazine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  venlafaxine On Formulary
Venlafaxine

The oral solution is non-formulary.

  Modified-release capsule
Efexor XL (Viatris UK Healthcare Ltd) Off Formulary
  Oral solution
Venlafaxine (Non-proprietary) Off Formulary
Nervous system / Attention deficit hyperactivity disorder
  atomoxetine Restricted
ATOMOXETINE

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

  dexamfetamine sulfate Restricted
Dexamfetamine

This is AS (is suitable for shared care) in the Black Country IMOG formulary. There is a RMOC ESCA available.

  guanfacine Restricted
Guanfacine

This is AS (is suitable for shared care) in the Black Country IMOG formulary. A RMOC ESCA is available.

  methylphenidate hydrochloride Restricted
METHYLPHENIDATE HYDROCHLORIDE

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability.

This is AS (is suitable for shared care) in the Black Country IMOG formulary. An RMOC ESCA is available

  Modified-release tablet
Concerta XL (Janssen-Cilag Ltd) Restricted
Delmosart (Accord-UK Ltd) Off Formulary
Matoride XL (Sandoz Ltd) Off Formulary
Ritalin-SR (Imported (United States)) Off Formulary
Xaggitin XL (Ethypharm UK Ltd) Off Formulary
Xenidate XL (Viatris UK Healthcare Ltd) Off Formulary
  Modified-release capsule
Equasym XL (Takeda UK Ltd) Off Formulary
Medikinet XL (Medice UK Ltd) Restricted
Nervous system / Depression
  agomelatine Restricted
Agomelatine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  amitriptyline hydrochloride On Formulary
  citalopram On Formulary
  clomipramine hydrochloride Senior pharmacist approval
  dosulepin hydrochloride Off Formulary
  doxepin Off Formulary
Doxepin

Consultant dermatologists - 3rd-line use only

  duloxetine On Formulary
DULOXETINE

Prescribe generically.

For urinary uses the 40 mg strength is the only product available.

 

  escitalopram On Formulary
ESCITALOPRAM

Second- or third-line use in anxiety. Prescibe generically.

  esketamine Off Formulary NICE TA854
  fluoxetine On Formulary
Fluoxetine

Prescribe generically.

  flupentixol Restricted
FLUPENTIXOL

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  fluvoxamine maleate Restricted
Fluvoxamine

This is Red (for hospital prescribing only) in the Black Country IMOG formulary following recommendation from the Mental Health team.

  imipramine hydrochloride On Formulary
  isocarboxazid Off Formulary
  lithium carbonate Restricted
LITHIUM CARBONATE

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

Any brand can be used but it must remain consistent.

  Modified-release tablet
Priadel (Essential Pharma Ltd) Off Formulary
  lithium citrate Restricted
LITHIUM CITRATE

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

Any brand can be used but it must remain consistent.

  Oral solution
Priadel (Essential Pharma Ltd) Off Formulary
  lofepramine On Formulary
  mianserin hydrochloride Off Formulary
  mirtazapine On Formulary
MIRTAZAPINE

The tablets are first-line, orodispersible tablets second-line and the oral solution third-line and very expensive.

  moclobemide Restricted
MOCLOBEMIDE

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  nortriptyline Restricted
Nortriptyline

The oral solution is Black in the Black Country IMOG formulary for neuropathic pain but allowed for hospital use as an antidepressant.

  paroxetine On Formulary
PAROXETINE

In liver impairment or third-line.

  phenelzine Restricted
Phenelzine

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  quetiapine Restricted
QUETIAPINE

Acute mania, add-on therapy for patients not responding to SSRIs in obsessive-compulsive disorder, and schizophrenia according to NICE guidelines

Treatment of delirium in intensive care (second-line use)

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary. The XL tablets are AR

  Modified-release tablet
Atrolak XL (Accord-UK Ltd) Off Formulary
Biquelle XL (Aspire Pharma Ltd) Off Formulary
Mintreleq XL (Aristo Pharma Ltd) Off Formulary
Seroquel XL (Luye Pharma Ltd) Off Formulary
Sondate XL (Teva UK Ltd) Off Formulary
Zaluron XL (Fontus Health Ltd) Off Formulary
  reboxetine Off Formulary
  sertraline On Formulary
  tranylcypromine Off Formulary
  trazodone hydrochloride On Formulary
Trazodone

Prescribe generically.

  trimipramine Off Formulary
  tryptophan Restricted
Tryptophan

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  venlafaxine On Formulary
Venlafaxine

The oral solution is non-formulary.

  Modified-release capsule
Efexor XL (Viatris UK Healthcare Ltd) Off Formulary
  Oral solution
Venlafaxine (Non-proprietary) Off Formulary
  vortioxetine Restricted NICE TA367
Vortioxetine

This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

For third-line use.

Nervous system / Psychoses and schizophrenia
  amisulpride Restricted
AMISULPRIDE

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  aripiprazole Restricted
ARIPIPRAZOLE

Please prescribe generically.

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary but the injection is Red.

  cariprazine Restricted
Cariprazine

This is Red (for hospital prescribing only) in the Black Country IMOG formulary and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  chlorpromazine hydrochloride Restricted
Chlorpromazine

In psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary and for nausea and labyrinth disorders it is Red.

  clozapine Restricted
CLOZAPINE

Initiation and maintenance by Mental Health team.

This is Red (for hospital prescribing only) in the Black Country IMOG formulary

  flupentixol Restricted
FLUPENTIXOL

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  flupentixol decanoate Restricted
FLUPENTIXOL DECANOATE

Psychiatrists.

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  haloperidol Restricted
Haloperidol

For treatment of psychoses and schizophrenia it is restricted to Psychiatrists.

This is AI (can be prescribed in primary care after specialist initiation) for psychoses and related disorders in the Black Country IMOG formulary and AR in nausea and vertigo and sssential tremor, chorea, tics, and related disorders.

It is Black for dystonia or or involuntary movement in Parkinsons Disease.

  Oral solution
Haldol (Essential Pharma Ltd) Off Formulary
  haloperidol decanoate Restricted
  loxapine Off Formulary
  lurasidone hydrochloride Restricted
Lurasidone

This is Red (for hospital prescribing only) in the Black Country IMOG formulary and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  olanzapine Restricted
OLANZAPINE

Acute mania and schizophrenia in accordance with NICE guidelines.
Treatment of delirium in intensive care (second-line use).

This is Red in the Black Country IMOG formulary, i.e. can only be prescribed in hospital and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  olanzapine embonate Restricted
OLANZAPINE EMBONATE

Acute mania and schizophrenia in accordance with NICE guidelines

 

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.


 

  paliperidone Restricted
Paliperidone

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

The oral form is for Mental Health use only and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  pericyazine Restricted
Pericyazine

This is AI (can be prescribed in primary care after specialist initiation by the Mental Health team) in the Black Country IMOG formulary.

  pimozide Off Formulary
  prochlorperazine On Formulary
Prochlorperazine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Prescribe generically.

  quetiapine Restricted
QUETIAPINE

Acute mania, add-on therapy for patients not responding to SSRIs in obsessive-compulsive disorder, and schizophrenia according to NICE guidelines

Treatment of delirium in intensive care (second-line use)

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary. The XL tablets are AR

  Modified-release tablet
Atrolak XL (Accord-UK Ltd) Off Formulary
Biquelle XL (Aspire Pharma Ltd) Off Formulary
Mintreleq XL (Aristo Pharma Ltd) Off Formulary
Seroquel XL (Luye Pharma Ltd) Off Formulary
Sondate XL (Teva UK Ltd) Off Formulary
Zaluron XL (Fontus Health Ltd) Off Formulary
  risperidone Restricted
RISPERIDONE

Acute mania, add-on therapy for patients who have not responded adequately to SSRIs in obsessive-compulsive disorder, and schizophrenia according to NICE guidelines.

For use in psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

The oral solution is second-line and the orodispersible tablet third-line.

  sulpiride Restricted
Sulpiride

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

The tablet is first line and the oral solution, which is very epxensive, is for those with swallowing difficulties only.

  trifluoperazine Restricted
Trifluoperazine

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  zuclopenthixol Restricted
Zuclopenthixol

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary but the solution for injection is Red.

  zuclopenthixol acetate Restricted
Zuclopenthixol acetate

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

  zuclopenthixol decanoate Restricted
Zuclopenthixol decanoate

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Nervous system / Bipolar disorder and mania
  aripiprazole Restricted
ARIPIPRAZOLE

Please prescribe generically.

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary but the injection is Red.

  asenapine Restricted
Asenapine

This is Red (for hospital prescribing only) in the Black Country IMOG formulary and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  carbamazepine Restricted
CARBAMAZEPINE

For psychoses and related disorders this is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary.

  Suppository
Carbamazepine (Non-proprietary) Off Formulary
  chlorpromazine hydrochloride Restricted
Chlorpromazine

In psychoses and related disorders this is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary and for nausea and labyrinth disorders it is Red.

  haloperidol On Formulary
  Oral solution
Haldol (Essential Pharma Ltd) Off Formulary
  lamotrigine On Formulary
Lamotrigine

Third-line use. Prescribe generically. This is AR (can be prescribed in primary care after specialist recommendation) in the Black Country IMOG formulary

 

 

  lithium carbonate Restricted
LITHIUM CARBONATE

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

Any brand can be used but it must remain consistent.

  Modified-release tablet
Priadel (Essential Pharma Ltd) Off Formulary
  lithium citrate Restricted
LITHIUM CITRATE

This is AS (is suitable for shared care) in the Black Country IMOG formulary.

Any brand can be used but it must remain consistent.

  Oral solution
Priadel (Essential Pharma Ltd) Off Formulary
  olanzapine Restricted
OLANZAPINE

Acute mania and schizophrenia in accordance with NICE guidelines.
Treatment of delirium in intensive care (second-line use).

This is Red in the Black Country IMOG formulary, i.e. can only be prescribed in hospital and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  paliperidone Restricted
Paliperidone

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

The oral form is for Mental Health use only and requires prior approval of the Black Country Healthcare NHS Foundation Trust.

  prochlorperazine On Formulary
Prochlorperazine

The injection is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Prescribe generically.

  quetiapine Restricted
QUETIAPINE

Acute mania, add-on therapy for patients not responding to SSRIs in obsessive-compulsive disorder, and schizophrenia according to NICE guidelines

Treatment of delirium in intensive care (second-line use)

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary. The XL tablets are AR

  Modified-release tablet
Atrolak XL (Accord-UK Ltd) Off Formulary
Biquelle XL (Aspire Pharma Ltd) Off Formulary
Mintreleq XL (Aristo Pharma Ltd) Off Formulary
Seroquel XL (Luye Pharma Ltd) Off Formulary
Sondate XL (Teva UK Ltd) Off Formulary
Zaluron XL (Fontus Health Ltd) Off Formulary
  sodium valproate Restricted
SODIUM VALPROATE

See MHRA guidance on prescribing 

https://www.gov.uk/guidance/valproate-use-by-women-and-girls

 

This is AR (can be prescribed in primary care after specialist recommendation) in men and women of non-childbearing potential in the Black Country IMOG formulary.

This is AS (is suitable for shared care) for use in women of childbearing potential and girls.

This is Red (for hospital prescribing only) in pregnancy, in women planning pregnancy an in women of childbearing potential where PREVENT applies, who decline or are unable to use effective contraception.

  valproic acid Restricted
VALPROIC ACID

Drug Safety Update January 2015

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  zuclopenthixol acetate Restricted
Zuclopenthixol acetate

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Nervous system / Inappropriate sexual behaviour
  benperidol Restricted
Benperidol

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Nervous system / Insomnia
  chloral hydrate Restricted
CHLORAL HYDRATE

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

NNU, or in line with childhood sedation policy.

  clomethiazole Off Formulary
  diazepam On Formulary
Diazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  flurazepam Off Formulary
  loprazolam Off Formulary
  lormetazepam Off Formulary
  melatonin Restricted
MELATONIN

Prescribe generically.

Slenyto is also approved for ASD and Smith-Magenis syndrome

 

  nitrazepam Off Formulary
  oxazepam Off Formulary
  promethazine hydrochloride On Formulary
Promethazine

Suitable for self-care/purchase, if appropriate, for short term use for insomnia, urticaria, allergies, and travel sickness.

  Oral tablet
Sominex (Dexcel-Pharma Ltd) Off Formulary
  temazepam On Formulary
Temazepam

For peri-operative sedation this is Red in the Black Country IMOC formulary, i.e for hospital prescribing only.

  zolpidem tartrate On Formulary NICE TA77
  zopiclone On Formulary NICE TA77
Nervous system / Narcolepsy
  dexamfetamine sulfate Restricted
Dexamfetamine

This is AS (is suitable for shared care) in the Black Country IMOG formulary. There is a RMOC ESCA available.

  methylphenidate hydrochloride Restricted
METHYLPHENIDATE HYDROCHLORIDE

Consultant Neurologists and Consultant Paediatricians specialising in neuro-disability.

This is AS (is suitable for shared care) in the Black Country IMOG formulary. An RMOC ESCA is available

  Modified-release tablet
Concerta XL (Janssen-Cilag Ltd) Restricted
Delmosart (Accord-UK Ltd) Off Formulary
Matoride XL (Sandoz Ltd) Off Formulary
Ritalin-SR (Imported (United States)) Off Formulary
Xaggitin XL (Ethypharm UK Ltd) Off Formulary
Xenidate XL (Viatris UK Healthcare Ltd) Off Formulary
  Modified-release capsule
Equasym XL (Takeda UK Ltd) Off Formulary
Medikinet XL (Medice UK Ltd) Restricted
  modafinil Restricted
MODAFINIL

This is AI (can be prescribed in primary care after specialist initiation) in the Black Country IMOG formulary.

  pitolisant Off Formulary
  sodium oxybate Off Formulary
Sodium oxybate

This is commssioned by NHSE for the indications below and a Blueteq form must be completed before prescribing. Please contact the Pharmacy High-Cost Drugs team if any assistance is required

Symptom control of narcolepsy with cataplexy in patients aged 7 to 18 years of age treated in a paediatric service

  solriamfetol Restricted NICE TA758
NICE TA777
Solriamfetol

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.

Nervous system / Sleep apnoea
  solriamfetol Restricted NICE TA758
NICE TA777
Solriamfetol

This is Red (for hospital prescribing only) in the Black Country IMOG formulary.