| Malignant disease | |||||
|---|---|---|---|---|---|
| Malignant disease / Antibody responsive malignancy | |||||
| atezolizumab [Specialist drug] | Hospital Only |
NICE TA525 NICE TA739 NICE TA520 NICE TA584 NICE TA705 NICE TA823 NICE TA638 NICE TA639 NICE TA666 |
|||
| avelumab [Specialist drug] | Hospital Only |
NICE TA517 NICE TA691 NICE TA645 NICE TA788 |
|||
| bevacizumab [Specialist drug] | Hospital Only |
NICE TA118 NICE TA212 NICE TA242 NICE TA178 NICE TA214 NICE TA263 NICE TA284 NICE TA285 NICE TA666 NICE TA946 |
|||
| Solution for infusion | |||||
| Avastin (Roche Products Ltd) | On Formulary | ||||
| blinatumomab [Specialist drug] | Hospital Only |
NICE TA450 NICE TA589 |
|||
| brentuximab vedotin [Specialist drug] | Hospital Only |
NICE TA478 NICE TA641 NICE TA524 NICE TA577 |
|||
| cetuximab [Specialist drug] | Hospital Only |
NICE TA145 NICE TA473 NICE TA242 NICE TA439 NICE TA668 |
|||
| Solution for infusion | |||||
| Erbitux (Merck Serono Ltd) | On Formulary | ||||
| daratumumab | Hospital Only |
NICE TA763 NICE TA783 NICE TA897 NICE TA917 NICE TA959 |
|||
| dinutuximab beta [Specialist drug] | Off Formulary |
NICE TA538 |
|||
| durvalumab [Specialist drug] | Hospital Only |
NICE TA798 NICE TA944 |
|||
| elotuzumab [Specialist drug] | Off Formulary | ||||
| gemtuzumab ozogamicin [Specialist drug] | Hospital Only |
NICE TA545 |
|||
| inotuzumab ozogamicin [Specialist drug] | Hospital Only |
NICE TA541 |
|||
| ipilimumab [Specialist drug] | Hospital Only |
NICE TA268 NICE TA319 NICE TA400 NICE TA716 NICE TA724 NICE TA780 NICE TA818 |
|||
| isatuximab [Specialist drug] | Hospital Only |
NICE TA658 |
|||
|
Approved by Cancer DTC
December 2020 |
|||||
| nivolumab [Specialist drug] | Hospital Only |
NICE TA384 NICE TA400 NICE TA684 NICE TA417 NICE TA780 NICE TA964 NICE TA462 NICE TA655 NICE TA713 NICE TA724 NICE TA876 NICE TA530 NICE TA817 NICE TA707 NICE TA746 NICE TA857 NICE TA865 NICE TA716 NICE TA736 NICE TA818 |
|||
| obinutuzumab [Specialist drug] | Hospital Only |
NICE TA343 NICE TA513 NICE TA629 |
|||
| panitumumab [Specialist drug] | Hospital Only |
NICE TA242 NICE TA439 |
|||
| pembrolizumab [Specialist drug] | Hospital Only |
NICE TA357 NICE TA366 NICE TA766 NICE TA837 NICE TA428 NICE TA531 NICE TA683 NICE TA770 NICE TA692 NICE TA772 NICE TA540 NICE TA967 NICE TA650 NICE TA830 NICE TA858 NICE TA661 NICE TA709 NICE TA914 NICE TA983 NICE TA737 NICE TA997 NICE TA801 NICE TA851 NICE TA939 NICE TA904 |
|||
| pertuzumab [Specialist drug] | Hospital Only |
NICE TA424 NICE TA509 NICE TA569 |
|||
| polatuzumab vedotin [Specialist drug] | Hospital Only |
NICE TA649 NICE TA874 |
|||
|
Approved by Cancer DTC
November 2020 |
|||||
| ramucirumab [Specialist drug] | Hospital Only |
NICE TA378 NICE TA403 |
|||
| rituximab | Hospital Only |
NICE TA308 NICE TA195 NICE TA243 NICE TA137 NICE TA193 NICE TA226 NICE TA174 NICE TA359 NICE TA561 |
|||
|
Rituximab-Connective Tissue Disease and Hypersensitivity Pneumonitis - Interstitial Lung Disease (CTD-ILD and HP-ILD) (November-2022)
NEL FPG Approved for use in Connective Tissue Disease- Interstitial Lung Disease (CTD-ILD) and Hypersensitivity Pneumonitis- Interstitial Lung Disease (HP-ILD) Treatment of Interstitial Lung Disease (ILD) in patients with severe active disease that has failed to respond to, or patient is intolerant to at least 2 immunosuppressants (tacrolimus, methotrexate, mycophenolate or cyclophosphamide), each having been taken for at least 3 months. Rituximab IV 1g on day 1 and day 15, then repeated 6 monthly if the patient responds. Hospital Only |
|||||
|
RENAL SERVICE
On Formulary for Idiopathic Membraneous Glomerulonephritis, biopsy-proven, steroid-sensitive minimal change nephropathy or primary focal segmental glomerulosclerosis (non-commissioned).
Renal Transplant Patients For vasculitis in renal transplant
|
|||||
|
Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adult
Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adults approved for use in May 2022 DTC as per Clinical Commissioning policy SSC2319 |
|||||
| Solution for infusion | |||||
| MabThera (Roche Products Ltd) | Hospital Only | ||||
| siltuximab | Off Formulary | ||||
| trastuzumab [Specialist drug] | Hospital Only |
NICE TA34 NICE TA257 NICE TA509 NICE TA208 |
|||
| Solution for injection | |||||
| Herceptin (Roche Products Ltd) | On Formulary | ||||
| trastuzumab emtansine [Specialist drug] | Hospital Only |
NICE TA458 NICE TA632 |
|||
| Malignant disease / Carcinoid syndrome | |||||
| telotristat ethyl | Off Formulary | ||||
| Malignant disease / Immunotherapy responsive malignancy | |||||
| Bacillus Calmette-Guérin [Specialist drug] | Hospital Only | ||||
| Powder for reconstitution for instillation | |||||
| OncoTICE (Merck Sharp & Dohme (UK) Ltd) | On Formulary | ||||
| aldesleukin [Specialist drug] | Hospital Only | ||||
| Powder for solution for injection | |||||
| Proleukin (Clinigen Healthcare Ltd) | Hospital Only | ||||
| interferon gamma-1b | Off Formulary | ||||
| lenalidomide [Specialist drug] | Hospital Only |
NICE TA322 NICE TA171 NICE TA586 NICE TA587 NICE TA627 NICE TA680 |
|||
| mifamurtide [Specialist drug] | Off Formulary |
NICE TA235 |
|||
| pomalidomide [Specialist drug] | Hospital Only |
NICE TA427 |
|||
|
Lenalidomide/Pomalidomide/Thalidomide Prescribing
see attached |
|||||
| talimogene laherparepvec [Specialist drug] | Hospital Only |
NICE TA410 |
|||
| thalidomide [Specialist drug] | Hospital Only |
NICE TA228 |
|||
|
Lenalidomide/Pomalidomide/Thalidomide Prescribing
see attached |
|||||
| Malignant disease / Targeted therapy responsive malignancy | |||||
| abemaciclib [Specialist drug] | Hospital Only |
NICE TA563 NICE TA725 NICE TA810 |
|||
| afatinib [Specialist drug] | Hospital Only |
NICE TA310 |
|||
| aflibercept [Specialist drug] | Hospital Only |
NICE TA294 NICE TA305 NICE TA346 NICE TA409 NICE TA486 NICE TA307 |
|||
| Solution for injection | |||||
| Eylea (Bayer Plc) | Hospital Only | ||||
| Solution for infusion | |||||
| Zaltrap (Sanofi) | Hospital Only | ||||
| alectinib [Specialist drug] | Hospital Only |
NICE TA536 |
|||
| axitinib [Specialist drug] | Hospital Only |
NICE TA333 NICE TA645 NICE TA650 |
|||
| binimetinib [Specialist drug] | Hospital Only |
NICE TA562 |
|||
| bortezomib [Specialist drug] | Hospital Only |
NICE TA370 NICE TA311 NICE TA228 NICE TA129 |
|||
| Powder for solution for injection | |||||
| Velcade (Janssen-Cilag Ltd) | On Formulary | ||||
| bosutinib [Specialist drug] | Hospital Only |
NICE TA401 |
|||
| brigatinib [Specialist drug] | Hospital Only |
NICE TA571 NICE TA670 |
|||
| cabozantinib [Specialist drug] | Hospital Only |
NICE TA463 NICE TA542 NICE TA964 NICE TA516 NICE TA928 NICE TA849 |
|||
| carfilzomib [Specialist drug] | Hospital Only |
NICE TA657 NICE TA695 |
|||
| ceritinib [Specialist drug] | Hospital Only |
NICE TA395 NICE TA500 |
|||
| cobimetinib [Specialist drug] | Hospital Only |
NICE TA414 |
|||
| crizotinib [Specialist drug] | Hospital Only |
NICE TA406 NICE TA422 NICE TA529 |
|||
| dabrafenib [Specialist drug] | Hospital Only |
NICE TA321 NICE TA396 NICE TA544 NICE TA898 |
|||
| dasatinib [Specialist drug] | Hospital Only |
NICE TA426 NICE TA425 |
|||
| encorafenib [Specialist drug] | Hospital Only |
NICE TA562 NICE TA668 |
|||
| erlotinib [Specialist drug] | Hospital Only |
NICE TA227 NICE TA258 NICE TA374 NICE TA374 |
|||
| everolimus | Hospital Only |
NICE TA421 NICE TA432 NICE TA449 |
|||
|
Afinitor® NICE TA498 Certican® NICE TA348 Certican® NICE TA481 |
|||||
| gefitinib [Specialist drug] | Hospital Only |
NICE TA192 NICE TA374 |
|||
| ibrutinib [Specialist drug] | Hospital Only |
NICE TA429 NICE TA891 NICE TA502 NICE TA795 |
|||
| idelalisib [Specialist drug] | Hospital Only |
NICE TA359 NICE TA604 |
|||
| imatinib [Specialist drug] | Hospital Only |
NICE TA326 NICE TA70 NICE TA86 NICE TA209 NICE TA426 NICE TA425 |
|||
| ixazomib [Specialist drug] | Hospital Only |
NICE TA870 |
|||
| lapatinib [Specialist drug] | Off Formulary |
NICE TA257 |
|||
| lenvatinib [Specialist drug] | Hospital Only |
NICE TA535 NICE TA551 NICE TA498 NICE TA858 NICE TA904 |
|||
| midostaurin [Specialist drug] | Hospital Only |
NICE TA523 NICE TA728 |
|||
| nilotinib [Specialist drug] | Hospital Only |
NICE TA426 NICE TA425 |
|||
| nintedanib | Hospital Only |
NICE TA347 NICE TA379 NICE TA864 NICE TA747 |
|||
| niraparib [Specialist drug] | Hospital Only |
NICE TA673 NICE TA784 |
|||
| olaparib [Specialist drug] | Hospital Only |
NICE TA908 NICE TA946 NICE TA962 NICE TA886 NICE TA887 NICE TA951 |
|||
| osimertinib [Specialist drug] | Hospital Only |
NICE TA653 NICE TA654 NICE TA761 |
|||
| palbociclib [Specialist drug] | Hospital Only |
NICE TA495 NICE TA836 |
|||
| pazopanib [Specialist drug] | Hospital Only |
NICE TA215 |
|||
| ponatinib [Specialist drug] | Hospital Only |
NICE TA451 |
|||
| regorafenib [Specialist drug] | Hospital Only |
NICE TA488 NICE TA555 NICE TA866 |
|||
| ribociclib [Specialist drug] | Hospital Only |
NICE TA496 NICE TA687 |
|||
| rucaparib [Specialist drug] | Hospital Only |
NICE TA1007 |
|||
| ruxolitinib [Specialist drug] | Hospital Only |
NICE TA386 NICE TA921 |
|||
| sorafenib [Specialist drug] | Hospital Only |
NICE TA178 NICE TA474 NICE TA535 |
|||
| sunitinib [Specialist drug] | Hospital Only |
NICE TA169 NICE TA179 NICE TA178 NICE TA449 |
|||
| temsirolimus [Specialist drug] | Hospital Only |
NICE TA178 |
|||
| tivozanib [Specialist drug] | Hospital Only |
NICE TA512 |
|||
| trametinib [Specialist drug] | Hospital Only |
NICE TA396 NICE TA544 |
|||
| vandetanib [Specialist drug] | Hospital Only |
NICE TA550 |
|||
| vemurafenib [Specialist drug] | Hospital Only |
NICE TA269 |
|||
| venetoclax [Specialist drug] | Hospital Only |
NICE TA561 NICE TA663 NICE TA796 NICE TA765 NICE TA787 |
|||
| vismodegib [Specialist drug] | Off Formulary |
NICE TA489 |
|||
| Malignant disease / Cytotoxic responsive malignancy | |||||
| DACTINOMYCIN | Hospital Only | ||||
| arsenic trioxide [Specialist drug] | Hospital Only |
NICE TA526 |
|||
| asparaginase [Specialist drug] | Hospital Only | ||||
| azacitidine [Specialist drug] | Hospital Only |
NICE TA218 NICE TA399 NICE TA827 |
|||
| bendamustine hydrochloride [Specialist drug] | Hospital Only |
NICE TA216 NICE TA472 |
|||
| bexarotene [Specialist drug] | Off Formulary | ||||
| bleomycin [Specialist drug] | Hospital Only | ||||
|
Bleomycin monitoring algorithm
Bleomycin monitoring algorithm |
|||||
| busulfan [Specialist drug] | Hospital Only | ||||
| cabazitaxel [Specialist drug] | Hospital Only |
NICE TA391 |
|||
| capecitabine [Specialist drug] | Hospital Only |
NICE TA263 NICE TA212 NICE TA191 NICE TA61 NICE TA100 |
|||
| carboplatin [Specialist drug] | Hospital Only |
NICE TA284 NICE TA285 |
|||
| carmustine [Specialist drug] | Hospital Only |
NICE TA121 |
|||
| chlorambucil [Specialist drug] | Hospital Only |
NICE TA343 NICE TA344 |
|||
| cisplatin [Specialist drug] | Hospital Only | ||||
| cladribine | Hospital Only |
NICE TA616 |
|||
| clofarabine [Specialist drug] | Hospital Only | ||||
| crisantaspase [Specialist drug] | Off Formulary | ||||
| cyclophosphamide | Hospital Only | ||||
| Powder for solution for injection | |||||
| Cyclophosphamide (Non-proprietary) | Hospital Only | ||||
| cytarabine [Specialist drug] | Hospital Only | ||||
| dacarbazine [Specialist drug] | Hospital Only | ||||
| Powder for solution for injection | |||||
| Dacarbazine (Non-proprietary) | On Formulary | ||||
| daunorubicin [Specialist drug] | Hospital Only | ||||
| daunorubicin with cytarabine [Specialist drug] | Hospital Only |
NICE TA552 |
|||
| decitabine [Specialist drug] | Hospital Only | ||||
| docetaxel [Specialist drug] | Hospital Only |
NICE TA101 NICE TA509 |
|||
| doxorubicin hydrochloride [Specialist drug] | Hospital Only |
NICE TA389 NICE TA465 |
|||
| epirubicin hydrochloride [Specialist drug] | Hospital Only | ||||
| eribulin [Specialist drug] | Hospital Only |
NICE TA423 NICE TA515 |
|||
| estramustine phosphate [Specialist drug] | Off Formulary | ||||
| etoposide [Specialist drug] | Hospital Only | ||||
| Powder for solution for injection | |||||
| Etopophos (Neon Healthcare Ltd) | On Formulary | ||||
|
Vinca alkaloids and etoposide
HOSPITAL ONLY |
|||||
| Solution for infusion | |||||
| Etoposide (Non-proprietary) | On Formulary | ||||
|
Vinca alkaloids and etoposide
HOSPITAL ONLY |
|||||
| fludarabine phosphate [Specialist drug] | Hospital Only |
NICE TA119 NICE TA29 |
|||
| fluorouracil | Hospital Only | ||||
| gemcitabine [Specialist drug] | Hospital Only |
NICE TA25 NICE TA116 NICE TA285 NICE TA389 NICE TA476 |
|||
| hydroxycarbamide | Hospital Only | ||||
| idarubicin hydrochloride [Specialist drug] | Hospital Only | ||||
| ifosfamide [Specialist drug] | Hospital Only | ||||
| Powder for solution for injection | |||||
| Ifosfamide (Non-proprietary) | On Formulary | ||||
| irinotecan hydrochloride [Specialist drug] | Hospital Only |
NICE TA440 |
|||
| lomustine [Specialist drug] | Hospital Only | ||||
| melphalan [Specialist drug] | Hospital Only | ||||
| Powder and solvent for solution for injection | |||||
| Melphalan (Non-proprietary) | Hospital Only | ||||
| mercaptopurine | Hospital Only | ||||
|
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines |
|||||
| methotrexate | Hospital Only | ||||
| mitomycin [Specialist drug] | Hospital Only | ||||
| mitotane [Specialist drug] | Hospital Only | ||||
| mitoxantrone [Specialist drug] | Hospital Only | ||||
| nelarabine [Specialist drug] | Hospital Only | ||||
| oxaliplatin [Specialist drug] | Hospital Only |
NICE TA100 NICE TA93 |
|||
| paclitaxel [Specialist drug] | Hospital Only |
NICE TA55 NICE TA284 NICE TA389 NICE TA476 |
|||
| panobinostat [Specialist drug] | Hospital Only |
NICE TA380 |
|||
| pegaspargase [Specialist drug] | Hospital Only |
NICE TA408 |
|||
| pemetrexed [Specialist drug] | Hospital Only |
NICE TA124 NICE TA181 NICE TA402 NICE TA190 NICE TA135 |
|||
| pentostatin [Specialist drug] | Hospital Only | ||||
| pixantrone [Specialist drug] | Hospital Only |
NICE TA306 |
|||
| procarbazine [Specialist drug] | Hospital Only | ||||
| raltitrexed [Specialist drug] | Hospital Only | ||||
| streptozocin [Specialist drug] | Hospital Only | ||||
| tegafur with gimeracil and oteracil [Specialist drug] | Hospital Only | ||||
| temozolomide [Specialist drug] | Hospital Only |
NICE TA23 NICE TA121 |
|||
| thiotepa [Specialist drug] | Hospital Only | ||||
| tioguanine [Specialist drug] | Hospital Only | ||||
| topotecan [Specialist drug] | Hospital Only |
NICE TA183 NICE TA184 NICE TA389 |
|||
|
June 2024 - Topotecan intravitreal injection – elevated doses in the treatment of paediatric retinoblastoma patients in BH
Topotecan intravitreal injection approved at NEL FPG for elevated doses in the treatment of paediatric retinoblastoma patients in Barts Health
Formulary Status: Hospital Only |
|||||
| trabectedin [Specialist drug] | Hospital Only |
NICE TA185 NICE TA389 |
|||
| treosulfan [Specialist drug] | Hospital Only |
NICE TA640 |
|||
| Powder for solution for injection | |||||
| Treosulfan (Non-proprietary) | On Formulary | ||||
| tretinoin [Specialist drug] | Hospital Only | ||||
| trifluridine with tipiracil [Specialist drug] | Hospital Only |
NICE TA405 NICE TA1008 NICE TA852 |
|||
| vinblastine sulfate [Specialist drug] | Hospital Only | ||||
| vincristine sulfate [Specialist drug] | Hospital Only | ||||
| vindesine sulfate [Specialist drug] | Hospital Only | ||||
| vinorelbine [Specialist drug] | Hospital Only | ||||
| Malignant disease / Cytotoxic drug-induced side effects | |||||
| dexrazoxane | Off Formulary | ||||
| folinic acid | Hospital Only |
NICE TA212 |
|||
| Solution for injection | |||||
| Folinic acid (Non-proprietary) | Hospital Only | ||||
| levofolinic acid | Hospital Only | ||||
| mesna | Hospital Only | ||||
| Solution for injection | |||||
| Mesna (Non-proprietary) | Hospital Only | ||||
| Malignant disease / Hyperuricaemia associated with cytotoxic drugs | |||||
| allopurinol | On Formulary | ||||
| febuxostat | On Formulary |
NICE TA164 |
|||
| rasburicase | On Formulary | ||||
| Powder and solvent for solution for infusion | |||||
| Fasturtec (Sanofi) | On Formulary | ||||
| Malignant disease / Hormone responsive malignancy | |||||
| abiraterone acetate | Hospital Only |
NICE TA259 NICE TA387 NICE TA721 |
|||
| bicalutamide | On Formulary | ||||
| buserelin | Hospital Only | ||||
| cyproterone acetate | On Formulary | ||||
| degarelix | On Formulary |
NICE TA404 |
|||
| Powder and solvent for solution for injection | |||||
| Firmagon (Ferring Pharmaceuticals Ltd) | On Formulary | ||||
| diethylstilbestrol | On Formulary | ||||
| enzalutamide | Hospital Only |
NICE TA316 NICE TA377 NICE TA580 NICE TA712 |
|||
| ethinylestradiol | Off Formulary | ||||
| flutamide | On Formulary | ||||
| goserelin | On Formulary | ||||
|
GOSERELIN
FOR HOSPITAL USE ONLY for All indications except for treatment of prostate cancer |
|||||
| lanreotide | Hospital Only | ||||
| leuprorelin acetate | Hospital Only | ||||
| Powder and solvent for suspension for injection | |||||
| Prostap 3 DCS (Takeda UK Ltd) | On Formulary | ||||
|
Prostap® 3 DCS
Endometriosis and fibroids (un-licensed) |
|||||
| Prostap SR DCS (Takeda UK Ltd) | On Formulary | ||||
| medroxyprogesterone acetate | On Formulary | ||||
| Suspension for injection | |||||
| Depo-Provera (Pfizer Ltd) | Hospital Only | ||||
| megestrol acetate | On Formulary | ||||
| norethisterone | Hospital Only | ||||
| octreotide | Hospital Only | ||||
| Solution for injection | |||||
| Octreotide (Non-proprietary) | Hospital Only | ||||
| Sandostatin (Novartis Pharmaceuticals UK Ltd) | Hospital Only | ||||
| Powder and solvent for suspension for injection | |||||
| Sandostatin LAR (Novartis Pharmaceuticals UK Ltd) | Hospital Only | ||||
| triptorelin | Hospital Only | ||||
| Malignant disease / Hormone responsive breast cancer | |||||
| anastrozole | On Formulary | ||||
| exemestane | On Formulary | ||||
| fulvestrant | On Formulary |
NICE TA503 |
|||
| Solution for injection | |||||
| Faslodex (AstraZeneca UK Ltd) | On Formulary | ||||
| letrozole | On Formulary | ||||
| tamoxifen | On Formulary | ||||
| Oral solution | |||||
| Tamoxifen (Non-proprietary) | On Formulary | ||||
| toremifene | Off Formulary | ||||
| Malignant disease / Photodynamic therapy responsive malignancy | |||||
| temoporfin [Specialist drug] | Hospital Only | ||||
| Malignant disease / Secondary bone metastases and hypercalcaemia | |||||
| calcitonin (salmon) | On Formulary | ||||
| Solution for injection | |||||
| Calcitonin (salmon) (Non-proprietary) | Hospital Only | ||||
| denosumab | Hospital Only |
NICE TA204 NICE TA265 |
|||
|
HOSPITAL ONLY USE
Skeletal related events in cancer |
|||||
|
Osteoporosis in postmenopausal women and in men at increased risk of fractures ( March 2022)
Approved in hospital for secondary prevention of osteoporosis in men and women 60 years or over, who meet the following inclusion criteria: 1. Patients with severe renal impairment. 2. Patients who are intolerant and with contraindications to bisphosphonate therapy. 3. Patients with severe vertebral osteoporosis. |
|||||
| Solution for injection | |||||
| Prolia (Amgen Ltd) | On Formulary | ||||
| Xgeva (Amgen Ltd) | On Formulary | ||||
| ibandronic acid | Off Formulary |
NICE TA464 |
|||
| pamidronate disodium | On Formulary | ||||
| Solution for infusion | |||||
| Pamidronate disodium (Non-proprietary) | On Formulary | ||||
|
PAMIDRONATE DISODIUM
FOR HOSPITAL USE ONLY |
|||||
| sodium clodronate | Hospital Only | ||||
| zoledronic acid | Hospital Only |
NICE TA464 |
|||
| Infusion | |||||
| Zometa (Phoenix Labs Ltd) | On Formulary | ||||
| Solution for infusion | |||||
| Zometa (Phoenix Labs Ltd) | On Formulary | ||||