| Gastro-intestinal system | |||||
|---|---|---|---|---|---|
| Gastro-intestinal system / Inflammatory bowel disease | |||||
| adalimumab | Hospital Only |
NICE TA187 NICE TA329 NICE TA199 NICE TA195 NICE TA375 NICE TA715 NICE TA383 NICE TA392 NICE TA146 NICE TA460 |
|||
| Solution for injection | |||||
| Humira (AbbVie Ltd) | Hospital Only | ||||
| Yuflyma (Celltrion Healthcare UK Ltd) | Hospital Only | ||||
| azathioprine | On Formulary | ||||
|
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines |
|||||
| balsalazide sodium | On Formulary | ||||
| beclometasone dipropionate | Off Formulary | ||||
| Modified-release tablet | |||||
| Clipper (Chiesi Ltd) | On Formulary | ||||
| ciclosporin | On Formulary |
NICE TA369 |
|||
| Oral solution | |||||
| Neoral (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
| Solution for infusion | |||||
| Sandimmun (Novartis Pharmaceuticals UK Ltd) | Hospital Only | ||||
| filgotinib | Hospital Only |
NICE TA676 NICE TA792 |
|||
|
Filgotinib for moderately to severely active ulcerative colitis in line with NICE TA792
Approved at July 2022 DTC for moderately to severely active ulcerative colitis in line with NICE TA792 |
|||||
| golimumab | Hospital Only |
NICE TA220 NICE TA375 NICE TA225 NICE TA383 NICE TA497 NICE TA329 |
|||
| Solution for injection | |||||
| Simponi (Merck Sharp & Dohme (UK) Ltd) | Hospital Only | ||||
| hydrocortisone | On Formulary | ||||
| infliximab | Hospital Only |
NICE TA134 NICE TA195 NICE TA375 NICE TA715 NICE TA199 NICE TA187 NICE TA163 NICE TA329 NICE TA383 |
|||
|
Adalimumab, Infliximab and Etanercept for moderate Rheumatoid arthritis – NICE TA 715-October 2021
The committee Approved the anti-TNFs onto the Barts Health Formulary, in accordance with NICE TA715. |
|||||
|
Use subcutaneous infliximab in patients with IBD, January 2021
Infliximab S/C in patients with IBD approved via chairs action on January 2021. |
|||||
| mercaptopurine | On Formulary | ||||
|
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines |
|||||
| mesalazine | On Formulary | ||||
| Modified-release tablet | |||||
| Mezavant XL (Takeda UK Ltd) | On Formulary | ||||
| Pentasa (Ferring Pharmaceuticals Ltd) | On Formulary | ||||
| Gastro-resistant tablet | |||||
| Octasa MR (Tillotts Pharma UK Ltd) | On Formulary | ||||
| Salofalk (Dr. Falk Pharma UK Ltd) | On Formulary | ||||
| Modified-release granules | |||||
| Pentasa (Ferring Pharmaceuticals Ltd) | On Formulary | ||||
| Salofalk (Dr. Falk Pharma UK Ltd) | On Formulary | ||||
| Suppository | |||||
| Pentasa (Ferring Pharmaceuticals Ltd) | On Formulary | ||||
| Salofalk (Dr. Falk Pharma UK Ltd) | On Formulary | ||||
| methotrexate | On Formulary | ||||
| mirikizumab | Hospital Only |
NICE TA925 |
|||
|
NICE TA 925 - December 2023 - Mirikizumab for treating moderately to severely active ulcerative colitis
Mirikizumab approved at NEL FPG for treating moderately to severely active ulcerative colitis in line with NICE TA. |
|||||
| ozanimod | Hospital Only |
NICE TA706 NICE TA828 |
|||
| prednisolone | On Formulary | ||||
| sulfasalazine | On Formulary | ||||
| tofacitinib | Hospital Only |
NICE TA480 NICE TA543 NICE TA920 NICE TA547 |
|||
|
NICE TA 920 - November 2023 – Tofacitinib for treating active ankylosing spondylitis
Tofacitinib approved at NEL FPG for treating active ankylosing spondylitis in line with NICE TA. |
|||||
| upadacitinib | Hospital Only |
NICE TA665 NICE TA744 NICE TA768 NICE TA829 NICE TA861 NICE TA814 NICE TA856 NICE TA905 |
|||
|
NICE TA 905 –July 2023, Upadacitinib for previously treated moderately to severely active Crohn’s disease
Upadacitnib approved at NEL FPG for previously treated moderately to severely active Crohn’s disease in line with NICE TA. |
|||||
|
NICE TA 856-Upadacitinib-Treating moderately to severely active ulcerative colitis
Upadacitinib approved at NEL FPG (March 23) for treating moderately to severely active ulcerative colitis in line with NICE TA 856, |
|||||
|
Upadacitinib (Rinvoq) for treating active non-radiographic axial spondyloarthritis, NICE TA 861, February 2023
Approved at NEL FPG for treating active non-radiographic axial spondyloarthritis. |
|||||
| ustekinumab | Hospital Only |
NICE TA180 NICE TA340 NICE TA456 NICE TA633 |
|||
|
June 2023 - Ustekinumab dose escalation in psoriasis
Ustekinumab approved at NEL FPG for dose escalation in psoriasis. Commissioned by the ICB under High Cost Drugs Pathway for Psoriasis • Patients ≤ 100 kg - Ustekinumab 45 mg SC every 12 weeks (licensed dose) may be increased to a maximum of 90 mg every 8 weeks • Patients >100kg - Ustekinumab 90 mg every 12 weeks (licensed dose) may be increased to a maximum of 90 mg every 8 weeks |
|||||
| vedolizumab | Hospital Only |
NICE TA352 NICE TA342 |
|||
| Gastro-intestinal system / Irritable bowel syndrome | |||||
| alverine citrate | On Formulary | ||||
| linaclotide | On Formulary | ||||
| mebeverine hydrochloride | On Formulary | ||||
| Modified-release capsule | |||||
| Mebeverine hydrochloride (Non-proprietary) | On Formulary | ||||
| Oral suspension | |||||
| Mebeverine hydrochloride (Non-proprietary) | On Formulary | ||||
| mebeverine with ispaghula husk | |||||
| Effervescent granules | |||||
| Fybogel Mebeverine (Reckitt Benckiser Healthcare (UK) Ltd) | On Formulary | ||||
|
Fybogel®
For palliative care use only |
|||||
| peppermint oil | On Formulary | ||||
| Gastro-intestinal system / Short bowel syndrome | |||||
| cimetidine | On Formulary | ||||
| teduglutide | Hospital Only |
NICE TA804 |
|||
| Gastro-intestinal system / Food allergy | |||||
| chlorphenamine maleate | On Formulary | ||||
| Oral solution | |||||
| Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
| Solution for injection | |||||
| Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
| sodium cromoglicate | On Formulary | ||||
| Gastro-intestinal system / Rectal and anal disorders | |||||
| diltiazem hydrochloride | Off Formulary | ||||
| Gastro-intestinal system / Anal fissures | |||||
| glyceryl trinitrate | On Formulary | ||||
| Rectal ointment | |||||
| Rectogesic (Kyowa Kirin International UK NewCo Ltd) | On Formulary | ||||
| lidocaine hydrochloride | Off Formulary | ||||
| Medicated plaster | |||||
| Ralvo (Grunenthal Ltd) | Off Formulary | ||||
| Versatis (Grunenthal Ltd) | Off Formulary | ||||
| Gastro-intestinal system / Haemorrhoids | |||||
| benzyl benzoate with bismuth oxide, bismuth subgallate, hydrocortisone acetate, peru balsam and zinc oxide | |||||
| Suppository | |||||
| Benzyl benzoate with bismuth oxide, bismuth subgallate, hydrocortisone acetate, peru balsam and zinc oxide (Non-proprietary) | On Formulary | ||||
| cinchocaine with hydrocortisone | On Formulary | ||||
| Suppository | |||||
| Proctosedyl (Phoenix Labs Ltd) | On Formulary | ||||
| Uniroid HC (Chemidex Pharma Ltd) | Off Formulary | ||||
| cinchocaine with prednisolone | |||||
| Suppository | |||||
| Scheriproct (Karo Pharma UK Ltd) | On Formulary | ||||
| hydrocortisone with lidocaine | Off Formulary | ||||
| phenol | On Formulary | ||||
| Gastro-intestinal system / Bowel cleansing | |||||
| Gastrografin | Hospital Only | ||||
| bisacodyl | Off Formulary | ||||
| docusate sodium | On Formulary | ||||
| macrogol 3350 with anhydrous sodium sulfate, ascorbic acid, potassium chloride, sodium ascorbate and sodium chloride | On Formulary | ||||
| magnesium citrate with sodium picosulfate | On Formulary | ||||
| magnesium sulfate | Off Formulary | ||||
| Gastro-intestinal system / Constipation | |||||
| DANTRON | Off Formulary | ||||
| arachis oil | On Formulary | ||||
| bisacodyl | On Formulary | ||||
| co-danthramer | |||||
| Oral suspension | |||||
| Co-danthramer (Non-proprietary) | On Formulary | ||||
| co-danthrusate | Off Formulary | ||||
| docusate sodium | On Formulary | ||||
| glycerol | On Formulary | ||||
| ispaghula husk | On Formulary | ||||
| lactulose | On Formulary | ||||
| Oral solution | |||||
| Lactulose (Non-proprietary) | On Formulary | ||||
| liquid paraffin | On Formulary | ||||
| Liquid | |||||
| Liquid paraffin (Non-proprietary) | On Formulary | ||||
| macrogol 3350 | On Formulary | ||||
| macrogol 3350 with potassium chloride, sodium bicarbonate and sodium chloride | On Formulary | ||||
| methylnaltrexone bromide | Hospital Only | ||||
| naloxegol | On Formulary |
NICE TA345 |
|||
| prucalopride | On Formulary |
NICE TA211 |
|||
| senna | On Formulary | ||||
| sodium acid phosphate with sodium phosphate | On Formulary | ||||
| sodium citrate | On Formulary | ||||
| sodium picosulfate | On Formulary | ||||
| Oral solution | |||||
| Sodium picosulfate (Non-proprietary) | On Formulary | ||||
| sterculia | Off Formulary | ||||
| sterculia with frangula | Off Formulary | ||||
| Gastro-intestinal system / Biliary disorders | |||||
| chenodeoxycholic acid | Hospital Only | ||||
| cholic acid | Hospital Only | ||||
| colestyramine | On Formulary | ||||
| obeticholic acid | Hospital Only |
NICE TA443 |
|||
| ursodeoxycholic acid | On Formulary | ||||
| Oral suspension | |||||
| Ursofalk (Dr. Falk Pharma UK Ltd) | On Formulary | ||||
| Gastro-intestinal system / Hepatic encephalopathy | |||||
| lactulose | On Formulary | ||||
| Oral solution | |||||
| Lactulose (Non-proprietary) | On Formulary | ||||
| Gastro-intestinal system / Oesophageal varices | |||||
| terlipressin acetate | Hospital Only | ||||
| Solution for injection | |||||
| Terlipressin acetate (Non-proprietary) | Hospital Only | ||||
| Glypressin (Ferring Pharmaceuticals Ltd) | Hospital Only | ||||
| vasopressin | On Formulary | ||||
| Solution for injection | |||||
| Vasopressin (Non-proprietary) | On Formulary | ||||
| Gastro-intestinal system / Obesity | |||||
| liraglutide | On Formulary |
NICE TA664 |
|||
|
Saxenda brand is HOSPITAL ONLY
This brand should only be prescribed under specialist supervision for patients under the care of tier 3 obesity services |
|||||
| Solution for injection | |||||
| Saxenda (Novo Nordisk Ltd) | On Formulary | ||||
| orlistat | On Formulary | ||||
| Gastro-intestinal system / Diarrhoea | |||||
| co-phenotrope | Off Formulary | ||||
| codeine phosphate | On Formulary | ||||
| colestyramine | On Formulary | ||||
| kaolin with morphine | Off Formulary | ||||
| loperamide hydrochloride | On Formulary | ||||
| loperamide with simeticone | Off Formulary | ||||
| Gastro-intestinal system / Gastro-intestinal smooth muscle spasm | |||||
| alverine citrate | On Formulary | ||||
| atropine sulfate | On Formulary | ||||
| Solution for injection | |||||
| Atropine sulfate (Non-proprietary) | On Formulary | ||||
| dicycloverine hydrochloride | On Formulary | ||||
| Oral solution | |||||
| Dicycloverine hydrochloride (Non-proprietary) | On Formulary | ||||
| dicycloverine hydrochloride with aluminium hydroxide, magnesium oxide and simeticone | Off Formulary | ||||
| hyoscine butylbromide | On Formulary | ||||
| mebeverine hydrochloride | On Formulary | ||||
| Modified-release capsule | |||||
| Mebeverine hydrochloride (Non-proprietary) | On Formulary | ||||
| Oral suspension | |||||
| Mebeverine hydrochloride (Non-proprietary) | On Formulary | ||||
| propantheline bromide | On Formulary | ||||
| Gastro-intestinal system / Exocrine pancreatic insufficiency | |||||
| pancreatin | On Formulary | ||||
| Gastro-resistant capsule | |||||
| Creon (Viatris UK Healthcare Ltd) | On Formulary | ||||
| Gastro-resistant granules | |||||
| Creon (Viatris UK Healthcare Ltd) | On Formulary | ||||
| Gastro-intestinal system / Dyspepsia | |||||
| alginic acid | Off Formulary | ||||
| co-magaldrox | On Formulary | ||||
| co-simalcite | Off Formulary | ||||
| magnesium carbonate | Off Formulary | ||||
| Gastro-intestinal system / Gastric and duodenal ulceration | |||||
| cimetidine | On Formulary | ||||
| esomeprazole | |||||
| Gastro-resistant capsule | |||||
| Esomeprazole (Non-proprietary) | On Formulary | ||||
| famotidine | On Formulary | ||||
| lansoprazole | On Formulary | ||||
| misoprostol | Hospital Only | ||||
| nizatidine | Off Formulary | ||||
|
On formulary during Ranitidine/Famotidine shortage
On Formulary during Ranitidine Shortage
Nizatidine may be used as an alternative during the Ranitidine supply shortage, but only for those patients where a PPI is not suitable, or where Cimetidine is not suitable due to interactions etc. See also Ranitidine page for Ranitidine shortage information in general. Agreed with DTC chair February 2020. |
|||||
| omeprazole | On Formulary | ||||
| pantoprazole | On Formulary | ||||
| ranitidine | On Formulary | ||||
|
H2 antagonist supply shortage
We are currently experiencing national supply issues of all H2-antagonists. All oral and IV formulations of ranitidine are out of stock, with no date for resupply until further notice. There is currently variable supplies of other H2-antagonist preparations (Cimetidine, Famotidine and Nizatidine). |
|||||
| sucralfate | On Formulary | ||||
| Gastro-intestinal system / Gastro-oesophageal reflux disease | |||||
| cimetidine | On Formulary | ||||
| esomeprazole | |||||
| Gastro-resistant capsule | |||||
| Esomeprazole (Non-proprietary) | On Formulary | ||||
| famotidine | On Formulary | ||||
| lansoprazole | On Formulary | ||||
| nizatidine | Off Formulary | ||||
|
On formulary during Ranitidine/Famotidine shortage
On Formulary during Ranitidine Shortage
Nizatidine may be used as an alternative during the Ranitidine supply shortage, but only for those patients where a PPI is not suitable, or where Cimetidine is not suitable due to interactions etc. See also Ranitidine page for Ranitidine shortage information in general. Agreed with DTC chair February 2020. |
|||||
| omeprazole | On Formulary | ||||
| pantoprazole | On Formulary | ||||
| sodium alginate with calcium carbonate and sodium bicarbonate | |||||
| Oral suspension | |||||
| Peptac (Teva UK Ltd) | On Formulary | ||||
| Gastro-intestinal system / Endoscopy | |||||
| Secretin Secrelux | On Formulary | ||||