Skin | |||||
---|---|---|---|---|---|
Skin / Gustatory sweating | |||||
propantheline bromide | On Formulary | ||||
Skin / Hyperhidrosis | |||||
aluminium chloride hexahydrate | On Formulary | ||||
botulinum toxin type A | On Formulary |
NICE TA260 NICE TA605 |
|||
Botox for patients undergoing abdominal reconstruction surgery
To relax the abdominal wall in preparation of abdominal wall reconstruction. 300 units to be administered 2 to 4 weeks before the procedure (300 units reconstituted in 150ml sodium chloride 0.9%) |
|||||
Botulinum toxin type A for the prevention of headaches in adults with chronic migraine
NICE Guidelines:Botulinum toxin type A for the prevention of headaches in adults with chronic migraine |
|||||
Overactive Bladder algorithm
Overactive Bladder algorithm |
|||||
Sialorrhoea
On Formulary - Approved for use in October 2019 at Drugs and Therapeutics Committee (DTC) - Xeomin brand ONLY
|
|||||
Powder for solution for injection | |||||
Azzalure (Galderma (UK) Ltd) | Off Formulary | ||||
Bocouture (Merz Pharma UK Ltd) | Off Formulary | ||||
Botox (AbbVie Ltd) | On Formulary | ||||
Dysport (Ipsen Ltd) | Hospital Only | ||||
Xeomin (Merz Pharma UK Ltd) | Off Formulary | ||||
Xeomin for Sialorrhea
On Formulary - Approved for use in October 2019 at Drugs and Therapeutics Committee (DTC) - Xeomin brand ONLY |
|||||
glycopyrronium bromide | On Formulary | ||||
Skin / Scalp and hair conditions | |||||
benzalkonium chloride | On Formulary | ||||
cetrimide with undecenoic acid | Off Formulary | ||||
coal tar | On Formulary | ||||
BAD specials, March 2020
These ‘specials’ are medications which are used in rare dermatological conditions and recommended by British Association of Dermatologists. Most of them are used due to no other availability of alternative products. These products will be restricted to only be prescribed by dermatologists within hospital, and not in primary care.
The Committee have agreed to add these to the Barts Health formulary, based on BAD’s recommendations. These will be restricted for use within Dermatology only. |
|||||
Shampoo | |||||
Polytar Scalp (Thornton & Ross Ltd) | On Formulary | ||||
coal tar with salicylic acid and precipitated sulfur | Off Formulary | ||||
ketoconazole | On Formulary | ||||
Skin / Alopecia | |||||
finasteride | On Formulary | ||||
minoxidil | On Formulary | ||||
Liquid | |||||
Minoxidil (Non-proprietary) | On Formulary | ||||
Regaine (Johnson & Johnson Ltd, McNeil Products Ltd) | On Formulary | ||||
Alopecia Pathway
Alopecia Pathway |
|||||
Skin / Hirsutism | |||||
co-cyprindiol | On Formulary | ||||
eflornithine | On Formulary | ||||
Skin / Superficial soft-tissue injuries and superficial thrombophlebitis | |||||
heparinoid | On Formulary | ||||
Skin / Dry and scaling skin disorders | |||||
barrier creams and ointments | On Formulary | ||||
emollient bath and shower products, antimicrobial-containing | On Formulary | ||||
emollient bath and shower products, paraffin-containing | |||||
Bath additive | |||||
Emollient bath and shower products, paraffin-containing (Non-proprietary) | On Formulary | ||||
Dermalo (Dermal Laboratories Ltd) | On Formulary | ||||
Dermalo®
First line choice |
|||||
Products without form | |||||
Emollient bath and shower products, paraffin-containing (Non-proprietary) | On Formulary | ||||
emollient creams and ointments, paraffin-containing | |||||
Liquid | |||||
Emollient creams and ointments, paraffin-containing (Non-proprietary) | On Formulary | ||||
QV®
Cream is a second line option emollient after Zerobase/ Diprobase/ Doublebase |
|||||
Skin / Acne | |||||
adapalene | On Formulary | ||||
adapalene with benzoyl peroxide | On Formulary | ||||
benzoyl peroxide | On Formulary | ||||
clindamycin | On Formulary | ||||
Solution for injection | |||||
Clindamycin (Non-proprietary) | On Formulary | ||||
Dalacin C (Pfizer Ltd) | On Formulary | ||||
co-cyprindiol | On Formulary | ||||
doxycycline | On Formulary | ||||
Modified-release capsule | |||||
Efracea (Galderma (UK) Ltd) | On Formulary | ||||
erythromycin | On Formulary | ||||
Gastro-resistant tablet | |||||
Erythromycin (Non-proprietary) | On Formulary | ||||
Oral suspension | |||||
Erythromycin (Non-proprietary) | On Formulary | ||||
erythromycin with zinc acetate | On Formulary | ||||
isotretinoin | Hospital Only | ||||
lymecycline | On Formulary | ||||
minocycline | Hospital Only | ||||
nicotinamide | Off Formulary | ||||
oxytetracycline | On Formulary | ||||
tretinoin with clindamycin | On Formulary | ||||
tretinoin with erythromycin | Off Formulary | ||||
Liquid | |||||
Aknemycin Plus (Almirall Ltd) | On Formulary | ||||
trimethoprim | On Formulary | ||||
Oral suspension | |||||
Trimethoprim (Non-proprietary) | On Formulary | ||||
Antibiotic prophylaxis in Urology 2014
Please see Microguide (App) |
|||||
TRIMETHOPRIM
Used for acne at a dose of 300mg twice daily for 4-8 weeks |
|||||
Skin / Rosacea | |||||
brimonidine tartrate | On Formulary | ||||
Skin / Sun protection and photodamage | |||||
fluorouracil | On Formulary | ||||
fluorouracil with salicylic acid | Off Formulary | ||||
ingenol mebutate | On Formulary | ||||
Skin / Warts and calluses | |||||
camellia sinensis | Off Formulary | ||||
formaldehyde | Off Formulary | ||||
imiquimod | On Formulary | ||||
podophyllotoxin | On Formulary | ||||
Liquid | |||||
Warticon (Phoenix Labs Ltd) | On Formulary | ||||
salicylic acid | On Formulary | ||||
salicylic acid with lactic acid | On Formulary | ||||
silver nitrate | On Formulary | ||||
Skin / Eczema and psoriasis | |||||
acitretin | Hospital Only | ||||
adalimumab | Hospital Only |
NICE TA187 NICE TA329 NICE TA199 NICE TA195 NICE TA375 NICE TA715 NICE TA383 NICE TA392 NICE TA146 NICE TA460 |
|||
Solution for injection | |||||
Humira (AbbVie Ltd) | Hospital Only | ||||
Yuflyma (Celltrion Healthcare UK Ltd) | Hospital Only | ||||
alitretinoin | Hospital Only |
NICE TA177 |
|||
Alitretinoin Capsules, Severe Chronic Hand Eczema, November 2008
Severe Chronic Hand Eczema in patients who are unresponsive to potent topical corticosteroids. |
|||||
apremilast | Hospital Only |
NICE TA433 NICE TA419 |
|||
azathioprine | On Formulary | ||||
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines |
|||||
beclometasone dipropionate | Off Formulary | ||||
betamethasone | On Formulary | ||||
Betesil Medicated Plaster - Inflammatory Skin Disorders (November 2022)
Approved at NEL FPG (Nov 2022) Betesil® 2.250mg medicated plaster is the only potent corticosteroid indicated in adults for the treatment of inflammatory skin disorders. The plaster is licensed to use for a maximum of 30 days at a time, with a maximum of 6 plasters being used at any one time. Plasters may be changed once every 24 hours. Amber-may be prescribed by or on the advice of a specialist |
|||||
Liquid | |||||
Betnovate (GlaxoSmithKline UK Ltd) | On Formulary | ||||
Diprosone (Organon Pharma (UK) Ltd) | On Formulary | ||||
betamethasone with clioquinol | On Formulary | ||||
betamethasone with fusidic acid | On Formulary | ||||
betamethasone with neomycin | Off Formulary | ||||
bimekizumab | Hospital Only |
NICE TA723 NICE TA916 NICE TA918 |
|||
NICE TA 918-November 2023-Bimekizumab for treating axial spondyloarthritis
Bimekizumab approved at NEL FPG for treating axial spondyloarthritis in line with NICE TA. |
|||||
Moderate to severe plaque psoriasis
Bimekizumab for treating moderate to severe plaque psoriasis- as per NICE TA 723. October 2021 DTC. |
|||||
NICE TA 916 - October 2023 - Bimekizumab for treating active psoriatic arthritis
Bimekizumab approved at NEL FPG for treating active psoriatic arthritis in line with NICE TA. |
|||||
brodalumab | Hospital Only |
NICE TA511 |
|||
calcipotriol | On Formulary | ||||
Liquid | |||||
Calcipotriol (Non-proprietary) | On Formulary | ||||
calcipotriol with betamethasone | On Formulary | ||||
calcitriol | On Formulary | ||||
certolizumab pegol | Hospital Only |
NICE TA375 NICE TA383 NICE TA415 NICE TA445 NICE TA574 |
|||
NICE TA574-Certolizumab pegol for treating moderate to severe plaque psoriasis
|
|||||
ciclosporin | On Formulary |
NICE TA369 |
|||
Oral solution | |||||
Neoral (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
Solution for infusion | |||||
Sandimmun (Novartis Pharmaceuticals UK Ltd) | Hospital Only | ||||
clobetasol propionate | On Formulary | ||||
Liquid | |||||
Dermovate (GlaxoSmithKline UK Ltd) | On Formulary | ||||
clobetasol propionate with neomycin sulfate and nystatin | Off Formulary | ||||
clobetasone butyrate | On Formulary | ||||
clobetasone butyrate with nystatin and oxytetracycline | On Formulary | ||||
coal tar | On Formulary | ||||
BAD specials, March 2020
These ‘specials’ are medications which are used in rare dermatological conditions and recommended by British Association of Dermatologists. Most of them are used due to no other availability of alternative products. These products will be restricted to only be prescribed by dermatologists within hospital, and not in primary care.
The Committee have agreed to add these to the Barts Health formulary, based on BAD’s recommendations. These will be restricted for use within Dermatology only. |
|||||
Shampoo | |||||
Coal tar (Non-proprietary) | On Formulary | ||||
Polytar Scalp (Thornton & Ross Ltd) | On Formulary | ||||
Cutaneous emulsion | |||||
Exorex (Teva UK Ltd) | On Formulary | ||||
coal tar with calamine | Off Formulary | ||||
coal tar with coconut oil and salicylic acid | Off Formulary | ||||
coal tar with dithranol and salicylic acid | Off Formulary | ||||
coal tar with salicylic acid | Off Formulary | ||||
coal tar with salicylic acid and precipitated sulfur | Off Formulary | ||||
coal tar with zinc oxide | Off Formulary | ||||
deucravacitinib | Hospital Only |
NICE TA907 |
|||
NICE TA 907- September 2023 - Deucravacitinib for treating moderate to severe plaque psoriasis
Deucravacitinib Approved at NEL FPG for treating moderate to severe plaque psoriasis in line with NICE TA. |
|||||
dimethyl fumarate | Hospital Only | ||||
Skilarence® NICE TA475 Tecfidera® NICE TA320 |
|||||
Gastro-resistant tablet | |||||
Skilarence (Almirall Ltd) | Hospital Only | ||||
Gastro-resistant capsule | |||||
Tecfidera (Biogen Idec Ltd) | On Formulary | ||||
dithranol | On Formulary | ||||
dithranol with salicylic acid and zinc oxide | Off Formulary | ||||
dupilumab | Hospital Only |
NICE TA534 NICE TA751 |
|||
etanercept | Hospital Only |
NICE TA103 NICE TA195 NICE TA375 NICE TA715 NICE TA199 NICE TA383 |
|||
Solution for injection | |||||
Benepali (Biogen Idec Ltd) | Hospital Only | ||||
Enbrel (Pfizer Ltd) | Hospital Only | ||||
Enbrel MyClic (Pfizer Ltd) | Off Formulary | ||||
Erelzi (Sandoz Ltd) | Off Formulary | ||||
Powder and solvent for solution for injection | |||||
Enbrel (Pfizer Ltd) | On Formulary | ||||
fludroxycortide | On Formulary | ||||
Impregnated dressing | |||||
Fludroxycortide (Non-proprietary) | On Formulary | ||||
fluocinolone acetonide | Hospital Only |
NICE TA301 NICE TA613 NICE TA590 |
|||
fluocinonide | Off Formulary | ||||
fluticasone | Off Formulary | ||||
guselkumab | Hospital Only |
NICE TA521 NICE TA815 |
|||
Guselkumab in Psoriatic Arthritis, NICE TA 815 (November 2022)
Guselkumab approved alone or with methotrexate, is recommended as an option for treating active psoriatic arthritis in adults whose disease has not responded well enough to disease-modifying antirheumatic drugs (DMARDs) or who cannot tolerate them. It is recommended only if they have had 2 conventional DMARDs and: |
|||||
Psoriatic arthritis
Approved for the treatment of active psoriatic arthritis after inadequate response to DMARDs as per NICE TA 711 September 2021 DTC |
|||||
hydrocortisone | On Formulary | ||||
hydrocortisone butyrate | Off Formulary | ||||
hydrocortisone with benzalkonium chloride, dimeticone and nystatin | On Formulary | ||||
hydrocortisone with chlorhexidine hydrochloride and nystatin | On Formulary | ||||
hydrocortisone with clotrimazole | On Formulary | ||||
hydrocortisone with fusidic acid | On Formulary | ||||
hydrocortisone with miconazole | On Formulary | ||||
hydrocortisone with oxytetracycline | Off Formulary | ||||
ichthammol | Off Formulary | ||||
ichthammol with zinc oxide | On Formulary | ||||
infliximab | Hospital Only |
NICE TA134 NICE TA195 NICE TA375 NICE TA715 NICE TA199 NICE TA187 NICE TA163 NICE TA329 NICE TA383 |
|||
Adalimumab, Infliximab and Etanercept for moderate Rheumatoid arthritis – NICE TA 715-October 2021
The committee Approved the anti-TNFs onto the Barts Health Formulary, in accordance with NICE TA715. |
|||||
Use subcutaneous infliximab in patients with IBD, January 2021
Infliximab S/C in patients with IBD approved via chairs action on January 2021. |
|||||
ixekizumab | Hospital Only |
NICE TA442 NICE TA537 NICE TA718 |
|||
Axial spondyloarthritis
Approved for treating axial spondyloarthritis as per NICE TA 718. Hospital Only. October 2021 DTC. |
|||||
methotrexate | On Formulary | ||||
mometasone furoate | On Formulary | ||||
Liquid | |||||
Elocon (Organon Pharma (UK) Ltd) | On Formulary | ||||
pimecrolimus | On Formulary |
NICE TA82 |
|||
salicylic acid with zinc oxide | On Formulary | ||||
secukinumab | Hospital Only |
NICE TA350 NICE TA407 NICE TA719 NICE TA445 NICE TA935 |
|||
NICE TA 935 - Secukinumab - Treating moderate to severe hidradenitis suppurativa
Secukinumab approved at NEL FPG for treating moderate to severe hidradenitis suppurativa in line with NICE TA Hospital Only |
|||||
Secukinumab dose escalation in psoriasis, April 2023
Approved at NEL-FPG in April 2023. Discount scheme applies until 2025. Commisioned by the ICB after this point as per the NEL High Cost Drug Pathway for Psoriasis Dose increased from 300mg once a month to 300mg fortnightly with a body weight of 90kg or higher. Patients who have an inadequate response after 3 months of dose escalation should be offered alternative treatment as per the NEL Psoriasis Pathway |
|||||
tacalcitol | Off Formulary | ||||
tacrolimus | Hospital Only |
NICE TA82 NICE TA481 NICE TA481 |
|||
tildrakizumab | Hospital Only |
NICE TA575 |
|||
NICE TA575- Tildrakizumab for treating moderate to severe plaque psoriasis
|
|||||
tralokinumab | Hospital Only |
NICE TA814 |
|||
Free of Charge Scheme for Severe Atopic dermatitis
Hospital Only FOC Scheme for severe atopic dermatitis- to be reviewed when NICE TA published. DTC Jan 2022 |
|||||
upadacitinib | Hospital Only |
NICE TA665 NICE TA744 NICE TA768 NICE TA829 NICE TA861 NICE TA814 NICE TA856 NICE TA905 |
|||
NICE TA 905 –July 2023, Upadacitinib for previously treated moderately to severely active Crohn’s disease
Upadacitnib approved at NEL FPG for previously treated moderately to severely active Crohn’s disease in line with NICE TA. |
|||||
NICE TA 856-Upadacitinib-Treating moderately to severely active ulcerative colitis
Upadacitinib approved at NEL FPG (March 23) for treating moderately to severely active ulcerative colitis in line with NICE TA 856, |
|||||
Upadacitinib for treating active ankylosing spondylitis, NICE TA 829 (November 2022)
Upadacitinib approved as an option for treating active ankylosing spondylitis that is not controlled well enough with conventional therapy in adults, only if tumour necrosis factor (TNF)-alpha inhibitors are not suitable or do not control the condition well enough. |
|||||
Upadacitinib (Rinvoq) for treating active non-radiographic axial spondyloarthritis, NICE TA 861, February 2023
Approved at NEL FPG for treating active non-radiographic axial spondyloarthritis. |
|||||
ustekinumab | Hospital Only |
NICE TA180 NICE TA340 NICE TA456 NICE TA633 |
|||
June 2023 - Ustekinumab dose escalation in psoriasis
Ustekinumab approved at NEL FPG for dose escalation in psoriasis. Commissioned by the ICB under High Cost Drugs Pathway for Psoriasis • Patients ≤ 100 kg - Ustekinumab 45 mg SC every 12 weeks (licensed dose) may be increased to a maximum of 90 mg every 8 weeks • Patients >100kg - Ustekinumab 90 mg every 12 weeks (licensed dose) may be increased to a maximum of 90 mg every 8 weeks |
|||||
Solution for injection | |||||
Stelara (Janssen-Cilag Ltd) | On Formulary | ||||
Skin / Urticaria | |||||
acrivastine | Off Formulary | ||||
alimemazine tartrate | Off Formulary | ||||
desloratadine | Off Formulary | ||||
fexofenadine hydrochloride | On Formulary | ||||
levocetirizine hydrochloride | Off Formulary | ||||
loratadine | On Formulary | ||||
Oral solution | |||||
Loratadine (Non-proprietary) | On Formulary | ||||
mizolastine | Off Formulary | ||||
omalizumab | Hospital Only |
NICE TA278 NICE TA339 |
|||
Solution for injection | |||||
Xolair (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
OMALIZUMAB
Only approved for specialist commissioned centres as per NHS specialist commissioning (currently approved centres are Barts Health, Royal Brompton and Guy's & St Thomas' for asthma and Barts Health is one of the centres for Chronic Spontaneous Urticaria) |
|||||
promethazine hydrochloride | On Formulary | ||||
Solution for injection | |||||
Phenergan (Sanofi Consumer Healthcare) | On Formulary | ||||
rupatadine | Off Formulary | ||||
Skin / Skin cleansers, antiseptics and desloughing agents | |||||
chlorhexidine | On Formulary | ||||
chlorhexidine gluconate with isopropyl alcohol | Off Formulary | ||||
chlorhexidine with cetrimide | Off Formulary | ||||
diethyl phthalate with methyl salicylate | Off Formulary | ||||
hydrogen peroxide | On Formulary | ||||
potassium permanganate | On Formulary | ||||
Tablet for cutaneous solution | |||||
Potassium permanganate (Non-proprietary) | On Formulary | ||||
Permitabs (Alliance Pharmaceuticals Ltd) | On Formulary | ||||
povidone-iodine | Off Formulary | ||||
proflavine | Off Formulary | ||||
Skin / Minor cuts and abrasions | |||||
glycerol with magnesium sulfate and phenol | Off Formulary | ||||
Skin / Pruritus | |||||
alimemazine tartrate | Off Formulary | ||||
calamine with zinc oxide | Off Formulary | ||||
cetirizine hydrochloride | On Formulary | ||||
Oral solution | |||||
Cetirizine hydrochloride (Non-proprietary) | On Formulary | ||||
chlorphenamine maleate | On Formulary | ||||
Oral solution | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
Solution for injection | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
coal tar with calamine | Off Formulary | ||||
crotamiton | On Formulary | ||||
difelikefalin | On Formulary |
NICE TA890 |
|||
NICE TA 890 - September 2023 - Difelikefalin for treating pruritus in people having haemodialysis
Difelikefalin approved at NEL FPG for treating pruritus in people having haemodialysis in line with NICE TA. |
|||||
doxepin | On Formulary | ||||
hydroxyzine hydrochloride | On Formulary | ||||
levocetirizine hydrochloride | Off Formulary | ||||
levomenthol | On Formulary | ||||
Skin / Bacterial skin infections | |||||
metronidazole | On Formulary | ||||
mupirocin | On Formulary | ||||
neomycin sulfate | Off Formulary | ||||
silver sulfadiazine | On Formulary | ||||
Skin / Fungal skin infections | |||||
amorolfine | |||||
Medicated nail lacquer | |||||
Amorolfine (Non-proprietary) | Off Formulary | ||||
Loceryl (Galderma (UK) Ltd) | Off Formulary | ||||
benzoic acid with salicylic acid | Off Formulary | ||||
chlorhexidine with nystatin | On Formulary | ||||
clotrimazole | On Formulary | ||||
Liquid | |||||
Canesten (Bayer Plc) | On Formulary | ||||
Spray | |||||
Canesten (Bayer Plc) | On Formulary | ||||
econazole nitrate | Off Formulary | ||||
griseofulvin | On Formulary | ||||
hydrocortisone with clotrimazole | On Formulary | ||||
ketoconazole | On Formulary | ||||
miconazole | On Formulary | ||||
Spray | |||||
Daktarin (Johnson & Johnson Ltd) | On Formulary | ||||
terbinafine | On Formulary | ||||
tioconazole | Off Formulary | ||||
undecenoic acid with zinc undecenoate | Off Formulary | ||||
Skin / Parasitic skin infections | |||||
benzyl benzoate | Off Formulary | ||||
dimeticone | Off Formulary | ||||
malathion | On Formulary | ||||
permethrin | On Formulary | ||||
Skin / Viral skin infections | |||||
aciclovir | On Formulary | ||||
Skin / Depigmentation | |||||
Hydroquinone | On Formulary | ||||
Isotretinoin- Isotrex gel | On Formulary | ||||
Monobenzone 20% cream | Hospital Only | ||||
Monobenzone 20% - 40% depigmenting cream
Available from GSTT NHS Trust as a special order: obtain approval from dermatology pharmacist |
|||||
Pigmanorm | Hospital Only | ||||
Tretinoin- Retin A | On Formulary | ||||
adapalene- Differin | On Formulary |